Dithiocarbamates and their complexes with transition metals have been used as common
pesticides, vulcanizing or analytical agents for decades. These compounds are one of the …

The modulation of apoptosis has emerged as an important weapon in the pathogenic
arsenal of multiple intracellular protozoan parasites. Cryptosporidium parvum, Leishmania …

Background Fluorescence Resonance Energy Transfer (FRET) between the green
fluorescent protein (GFP) variants CFP and YFP is widely used for the detection of protein …

Chronic inflammatory lung diseases are characterized by increased expression of multiple
inflammatory genes following activation by proinflammatory transcription factors, such as …

We describe here the X-ray crystal structure of NF-κB p50/RelB heterodimer bound to a κB
DNA. Although the global modes of subunit association and κB DNA recognition are similar …

Ricin is a potential bioweapon because of its toxicity, availability, and ease of production.
When delivered to the lungs, ricin causes severe pulmonary damage with symptoms that are …

Synthesis and structure–activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-β
inhibitors - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …

Abstract CP-1/CCL2 (monocyte chemoattractant protein-1/CC chemokine ligand 2) is a β or
CC chemokine that is expressed by a variety of cell types, including fibroblasts, endothelial …

Previously, we have shown by sensitivity analysis, that the oscillatory behavior of nuclear
factor (NF‐κB) is coupled to free IkappaB kinase‐2 (IKK2) and IkappaBalpha (IκBα), and that …

转录调节因子核因子(NF-κB) 的活化与灭活, 直接参与调节多种与急性肺损伤(ALI)
相关的炎性细胞因子及黏附因子的基因转录. NF-κB 的活化与炎性细胞因子的表达及肺损伤之间 …