Primary liver cancer, which consists predominantly of hepatocellular carcinoma (HCC), is
the fifth most common cancer worldwide and the third most common cause of cancer …

Virus-like particles (VLPs) consist of viral structural proteins that, when overexpressed,
spontaneously self-assemble into particles that are antigenically indistinguishable from …

Hepatitis B virus (HBV) infection is a worldwide health problem and may cause acute,
fulminant, chronic hepatitis, liver cirrhosis, or hepatocelullar carcinoma (HCC). Infection with …

Background & Aims: Following the world's first successful implementation of a universal
hepatitis B virus (HBV) vaccination program for infants in Taiwan 20 years ago, we …

The increasing level of disease control by vaccination jointly with the growing standard of
living and health of modern societies could favour the spread of exemption as a “rational” …

BACKGROUND/PURPOSE: Taiwan is a hyperendemic area of liver diseases. Hepatitis B
virus (HBV) and hepatitis C virus (HCV) are the two major etiologies of liver diseases in …

Background & Aims: The study objective was to determine the risk of all-cause and cause-
specific mortality as well as to examine the predictors of mortality in chronic hepatitis B …

For adolescents, the transition from childhood to adult status is both difficult and stressful. As
such, many experience ambivalence and physical and emotional turmoil, which threaten …

Chronic hepatitis B virus (HBV) infection is the primary risk factor for the development of
hepatocellular carcinoma worldwide. After decades of chronic hepatitis, about 30-40% of …

Background. Chronic hepatitis B seems to manifest as mild disease in children and young
adults. However, data regarding the long-term course of hepatitis B in untreated and …