Is HIV-1 evolving to a less virulent form in humans?

KK Ariën, G Vanham, EJ Arts - Nature Reviews Microbiology, 2007 - nature.com
During the rapid spread of HIV-1 in humans, the main (M) group of HIV-1 has evolved into
ten distinct subtypes, undergone countless recombination events and diversified …

HIV genetic diversity: biological and public health consequences

IF Butler, I Pandrea, PA Marx, C Apetrei - Current HIV research, 2007 - ingentaconnect.com
The devastating consequences of AIDS pandemic will probably only be controlled when a
vaccine is developed that is safe, effective, affordable, and simple enough to permit …

Chronic HIV-1 infection frequently fails to protect against superinfection

A Piantadosi, B Chohan, V Chohan… - PLoS …, 2007 - journals.plos.org
Reports of HIV-1 superinfection (re-infection) have demonstrated that the immune response
generated against one strain of HIV-1 does not always protect against other strains …

Generation and immunogenicity of novel HIV/AIDS vaccine candidates targeting HIV-1 Env/Gag-Pol-Nef antigens of clade C

CE Gómez, JL Nájera, V Jiménez, K Bieler, J Wild… - Vaccine, 2007 - Elsevier
Recombinants based on the attenuated vaccinia virus strains MVA and NYVAC are
considered candidate vectors against different human diseases. In this study we have …

Evaluation of two commercially available alternatives for HIV-1 viral load testing in resource-limited settings

K Steegen, S Luchters, N De Cabooter… - Journal of virological …, 2007 - Elsevier
There is an urgent need for low-cost assays for HIV-1 quantitation to ensure adequate follow-
up of HIV-infected patients on antiretroviral therapy (ART) in resource-limited countries. Two …

High levels of primary antiretroviral resistance genotypic mutations and B/F recombinants in Santos, Brazil

MCA Sucupira, MM Caseiro, K Alves… - AIDS patient care and …, 2007 - liebertpub.com
This study characterized HIV-1 among antiretroviral-naïve populations presenting recent
infection (RI) or long-standing infection (LSI). Sera collected from January 1999 to …

Molecular epidemiology of HIV type 1 in treatment-naive patients in north Ethiopia

A Kassu, M Fujino, M Matsuda… - AIDS research and …, 2007 - liebertpub.com
To understand the predominant HIV subtype and drug-resistant viruses in northwest
Ethiopia, isolates from 92 antiretroviral drug-naive HIV-1-infected tuberculosis patients were …

The complexity of circulating HIV type 1 strains in Oyo state, Nigeria

JL Sankalé, S Langevin, G Odaibo… - AIDS research and …, 2007 - liebertpub.com
Multiple HIV-1 subtypes and circulating recombinant forms (CRFs) are known to circulate in
West Africa. We undertook a survey of HIVs in Oyo state, in southwestern Nigeria. We …

Primary isolates of human immunodeficiency virus type 1 are usually dominated by the major variants found in blood

Y Voronin, B Chohan, M Emerman… - Journal of virology, 2007 - Am Soc Microbiol
The isolation of primary strains of human immunodeficiency virus (HIV) is an invaluable tool
for assessing properties of viruses replicating in HIV-infected subjects. A common method …

[HTML][HTML] Complex patterns of the HIV-1 epidemic in Kuala Lumpur, Malaysia: evidence for expansion of circulating recombinant form CRF33_01B and detection of …

B Wang, KA Lau, LY Ong, M Shah, MC Steain, B Foley… - Virology, 2007 - Elsevier
The HIV protease-reverse transcriptase (PR-RT)(1047 bp), gp120-env (891 bp) and gp41-
env (547 bp) regions from the plasma of 115 HIV-1-infected patients in Kuala Lumpur (KL) …