Amyloids are filamentous protein deposits ranging in size from nanometres to microns and
composed of aggregated peptide β-sheets formed from parallel or anti-parallel alignments of …

Aggregation of α-synuclein (α-syn) has been linked to the pathogenesis of Parkinson's
disease (PD) and other neurodegenerative diseases. Increasing evidence suggests that …

Abstract α-synuclein is a major component of intraneuronal protein aggregates constituting a
distinctive feature of Parkinson disease. To date, fluorescence imaging of dynamic …

Elucidating the details of the assembly of amyloid fibrils is a key step to understanding the
mechanism of amyloid deposition diseases including Parkinson's disease. Although several …

The synuclein family of intrinsically unfolded proteins is composed of three highly
homologous members, α-synuclein (αS), β-synuclein (βS) and γ-synuclein (γS), which are …

Abstract α-Synuclein filaments are the central component of intracytoplasmic inclusion
bodies characteristic of Parkinson's disease (PD) and related disorders. Metals are the …

α-Synuclein conformational modulation leading to fibrillation has been centrally implicated
in Parkinson's disease. Previously, we have shown that α-synuclein has DNA binding …

α-Synuclein filaments are the central component of intracytoplasmic inclusion bodies
characteristic of Parkinson's disease (PD) and related disorders. Metals are the significant …

Accumulation of chemically altered proteins is a noted characteristic of biological aging, and
increasing evidence suggests a variety of deleterious cellular developments associated with …

Exploiting the concepts learnt from nature to build new nanomaterials from the bottom up is
critical for the efficient design of complex nanodevices. We demonstrate for the first time that …