Embryonic stem cells (ESCs) are a potential source of neural derivatives that can be used in
stem cell‐based therapies designed to treat neurological disorders. The derivation of …

We cannot catechise our stony ichthyolites, as did the necromantic lady of the Arabian
Nights did the coloured fishes of the lake which had once been a city, when she touched …

Kremen 1 and 2 (Krm1/2) are transmembrane receptors for Wnt antagonists of the Dickkopf
(Dkk) family and function by inhibiting the Wnt co-receptors LRP5/6. Here we show that …

We present a loss‐of‐function study using antisense morpholino (MO) reagents for the
organizer‐specific gene Goosecoid (Gsc) and the ventral genes Vent1 and Vent2. Unlike in …

Fetal alcohol spectrum disorder (FASD) is the combination of developmental, morphological,
and neurological defects that result from exposing human embryos to ethanol (EtOH) …

Signaling centers or organizers play a key role in axial patterning processes in animal
embryogenesis. The function of most vertebrate organizers involves the activity of secreted …

Eye induction and eye field separation are the earliest events during vertebrate eye
development. Both of these processes occur much earlier than the formation of optic …

Background Cell-cell communication is essential in tissue patterning. In early amphibian
development, mesoderm is formed in the blastula-stage embryo through inductive …

Inca (induced in neural crest by AP2) is a novel protein discovered in a microarray screen for
genes that are upregulated in Xenopus embryos by the transcriptional activator protein …

Embryonic stem cells (ES cells) can give rise to a broad spectrum of neural cell types. The
biomedical application of ES cells will require detailed knowledge on the role of individual …