A serious disorder with characteristic microvascular thrombosis involving the brain and other
organs, thrombotic thrombocytopenic purpura (TTP) typically presents with …

Both hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are
characterized by thrombotic microangiopathy (TMA), affecting mainly the kidney and brain …

Thrombotic thrombocytopenic purpura (TTP) is a life‐threatening disorder and plasma
exchange (PEX) remains the primary treatment modality. Twenty‐five patients with acute …

To study both the pathophysiologic and the prognostic value of ADAMTS13 in thrombotic
microangiopathies (TMAs), we enrolled a cohort of 35 adult patients combining a first acute …

The last 10 years witnessed the publication of many studies on the pathophysiology of
thrombotic thrombocytopenic purpura (TTP), a life-threatening disease characterized by …

Thrombotic thrombocytopenic purpura (TTP) is a severe multisystem thrombotic
microangiopathy (TMA). Significant advances have been made in understanding the …

An international working group of clinicians and pathologists met in 2003 under the
auspices of the International Society of Nephrology (ISN) and the Renal Pathology Society …

Background A 19-year-old woman with newly diagnosed systemic lupus erythematosus
(SLE) presented with hemolytic anemia, thrombocytopenia, hypertension, tonic-clonic …

The activity of ADAMTS13, the von Willebrand factor cleaving protease, is deficient in
patients with thrombotic thrombocytopenic purpura (TTP). In the present study, the …

Study of ADAMTS13 has exploded since this metalloprotease was characterized. This
knowledge reveals the nature of ADAMTS13's interaction with von Willebrand factor and the …