Thrombotic thrombocytopenic purpura: a thrombotic disorder caused by ADAMTS13 deficiency
HM Tsai - Hematology/oncology clinics of North America, 2007 - Elsevier
A serious disorder with characteristic microvascular thrombosis involving the brain and other
organs, thrombotic thrombocytopenic purpura (TTP) typically presents with …
organs, thrombotic thrombocytopenic purpura (TTP) typically presents with …
Does hemolytic uremic syndrome differ from thrombotic thrombocytopenic purpura?
F Fakhouri, V Frémeaux-Bacchi - Nature clinical practice Nephrology, 2007 - nature.com
Both hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are
characterized by thrombotic microangiopathy (TMA), affecting mainly the kidney and brain …
characterized by thrombotic microangiopathy (TMA), affecting mainly the kidney and brain …
Remission in acute refractory and relapsing thrombotic thrombocytopenic purpura following rituximab is associated with a reduction in IgG antibodies to ADAMTS‐13
Thrombotic thrombocytopenic purpura (TTP) is a life‐threatening disorder and plasma
exchange (PEX) remains the primary treatment modality. Twenty‐five patients with acute …
exchange (PEX) remains the primary treatment modality. Twenty‐five patients with acute …
Prognostic value of anti-ADAMTS13 antibody features (Ig isotype, titer, and inhibitory effect) in a cohort of 35 adult French patients undergoing a first episode of …
S Ferrari, F Scheiflinger, M Rieger, G Mudde, M Wolf… - Blood, 2007 - ashpublications.org
To study both the pathophysiologic and the prognostic value of ADAMTS13 in thrombotic
microangiopathies (TMAs), we enrolled a cohort of 35 adult patients combining a first acute …
microangiopathies (TMAs), we enrolled a cohort of 35 adult patients combining a first acute …
TTP and ADAMTS13: when is testing appropriate?
PM Mannucci, F Peyvandi - ASH Education Program Book, 2007 - ashpublications.org
The last 10 years witnessed the publication of many studies on the pathophysiology of
thrombotic thrombocytopenic purpura (TTP), a life-threatening disease characterized by …
thrombotic thrombocytopenic purpura (TTP), a life-threatening disease characterized by …
Reduced von Willebrand factor-cleaving protease levels in secondary thrombotic microangiopathies and other diseases
M Franchini, M Montagnana… - … in thrombosis and …, 2007 - thieme-connect.com
Thrombotic thrombocytopenic purpura (TTP) is a severe multisystem thrombotic
microangiopathy (TMA). Significant advances have been made in understanding the …
microangiopathy (TMA). Significant advances have been made in understanding the …
The pathology of lupus nephritis
MM Schwartz - Seminars in nephrology, 2007 - Elsevier
An international working group of clinicians and pathologists met in 2003 under the
auspices of the International Society of Nephrology (ISN) and the Renal Pathology Society …
auspices of the International Society of Nephrology (ISN) and the Renal Pathology Society …
Thrombotic microangiopathic hemolytic anemia in a patient with SLE: diagnostic difficulties
AA Shah, JP Higgins, EF Chakravarty - Nature clinical practice …, 2007 - nature.com
Background A 19-year-old woman with newly diagnosed systemic lupus erythematosus
(SLE) presented with hemolytic anemia, thrombocytopenia, hypertension, tonic-clonic …
(SLE) presented with hemolytic anemia, thrombocytopenia, hypertension, tonic-clonic …
ADAMTS13 phenotype in plasma from normal individuals and patients with thrombotic thrombocytopenic purpura
M Manea, AC Kristoffersson, HM Tsai, W Zhou… - European journal of …, 2007 - Springer
The activity of ADAMTS13, the von Willebrand factor cleaving protease, is deficient in
patients with thrombotic thrombocytopenic purpura (TTP). In the present study, the …
patients with thrombotic thrombocytopenic purpura (TTP). In the present study, the …
Structural and functional correlation of ADAMTS13
J Dong - Current opinion in hematology, 2007 - journals.lww.com
Study of ADAMTS13 has exploded since this metalloprotease was characterized. This
knowledge reveals the nature of ADAMTS13's interaction with von Willebrand factor and the …
knowledge reveals the nature of ADAMTS13's interaction with von Willebrand factor and the …