Viral suppression of the interferon system

F Weber, O Haller - Biochimie, 2007 - Elsevier
Type I interferons (IFN-α/β) were originally discovered by their strong and direct antiviral
activity [A. Isaacs, J. Lindenmann, Virus interference. I. The interferon, Proc. R. Soc. Lond. B …

[HTML][HTML] Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines

R Züst, L Cervantes-Barragán, T Kuri, G Blakqori… - PLoS …, 2007 - journals.plos.org
Attenuated viral vaccines can be generated by targeting essential pathogenicity factors. We
report here the rational design of an attenuated recombinant coronavirus vaccine based on …

The influenza virus NS1 protein: inhibitor of innate and adaptive immunity

A Fernandez-Sesma - Infectious Disorders-Drug Targets …, 2007 - ingentaconnect.com
The influenza virus NS1 protein has been shown to be a multifunctional immune modulator
and a virulence factor for this virus. Among its multiple functions are the inhibition of the type …

Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine

AL Vincent, W Ma, KM Lager, BH Janke, RJ Webby… - Vaccine, 2007 - Elsevier
In the US, despite available swine influenza virus (SIV) vaccines, multiple influenza
subtypes as well as antigenic and genetic variants within subtypes continue to circulate in …

Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus

CR Baskin, H Bielefeldt-Ohmann… - Journal of …, 2007 - Am Soc Microbiol
We are still inadequately prepared for an influenza pandemic due to the lack of a vaccine
effective for subtypes to which the majority of the human population has no prior immunity …

Pathogenesis and inflammatory responses of swine H1N2 influenza viruses in pigs

SK Jo, HS Kim, SW Cho, SH Seo - Virus research, 2007 - Elsevier
Swine influenza viruses are an important pathogen in pig industry. In this study, we wanted
to know whether swine H1N2 influenza viruses circulating in Korean pigs would cause …

A 型流感病毒NS1 蛋白研究进展

李建丽, 张万坡, 毕丁仁 - 微生物学报, 2007 - cqvip.com
NS1 蛋白是A 型流感病毒的唯一的非结构蛋白, 是一种RNA 结合蛋白, 具有重要的调节活性.
NS1 蛋白仅存在于病毒感染的细胞内, 且在感染的早期, 大量存在于细胞核中, 而在感染的晚期 …

[PDF][PDF] Non-contact measurement of soil moisture content using thermal infrared sensor and weather variables

T Alshikaili - 2007 - harvest.usask.ca
The use of remote sensing technology has made it possible for the non-contact
measurement of soil moisture content (SMC). Many remote sensing techniques can be used …

Role of the influenza virus nonstructural 1 protein in evasion of immunity

A Fernandez-Sesma, TM Moran - Future Virology, 2007 - Taylor & Francis
The influenza virus nonstructural (NS) 1 protein is a potent immune modulator that has
multiple inhibitory functions in the infected cells. The NS1 protein blocks the production of …

Opinion of the Scientific Panel on Animal Health and Welfare (AHAW) related with the vaccination against avian influenza of H5 and H7 subtypes in domestic poultry …

European Food Safety Authority (EFSA) - EFSA Journal, 2007 - Wiley Online Library
Since the emergence of the HPAI strain of H5N1 in South East Asia and its westward
spread, the prevention and control methods are under scrutiny in many parts of the world …