A review of human vaccine research and development: malaria
MP Girard, ZH Reed, M Friede, MP Kieny - Vaccine, 2007 - Elsevier
The last several years have seen significant progress in the development of vaccines
against malaria. Most recently, proof-of-concept of vaccine-induced protection from malaria …
against malaria. Most recently, proof-of-concept of vaccine-induced protection from malaria …
Long-term clinical protection from falciparum malaria is strongly associated with IgG3 antibodies to merozoite surface protein 3
C Roussilhon, C Oeuvray, C Müller-Graf, A Tall… - PLoS …, 2007 - journals.plos.org
Background Surrogate markers of protective immunity to malaria in humans are needed to
rationalize malaria vaccine discovery and development. In an effort to identify such markers …
rationalize malaria vaccine discovery and development. In an effort to identify such markers …
Plasmodium falciparum Merozoite Surface Protein 3 Is a Target of Allele-Specific Immunity and Alleles Are Maintained by Natural Selection
SD Polley, KKA Tetteh, JM Lloyd… - The Journal of …, 2007 - academic.oup.com
Background Plasmodium falciparum merozoite surface protein (MSP) 3 is an asexual blood-
stage malaria vaccine candidate antigen. Sequence polymorphisms divide alleles into 2 …
stage malaria vaccine candidate antigen. Sequence polymorphisms divide alleles into 2 …
A novel antibody-dependent cellular cytotoxicity mechanism involved in defense against malaria requires costimulation of monocytes FcγRII and FcγRIII
A Jafarshad, MH Dziegiel, R Lundquist… - The Journal of …, 2007 - journals.aai.org
Clinical experiments have shown that the Ab-dependent cell-mediated inhibition of
Plasmodium falciparum is a major mechanism controlling malaria parasitemia and thereby …
Plasmodium falciparum is a major mechanism controlling malaria parasitemia and thereby …
Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial
CC Hermsen, DF Verhage, DSC Telgt, K Teelen… - Vaccine, 2007 - Elsevier
The glutamate-rich protein (GLURP) of P. falciparum is the target of cytophilic antibodies
which are significantly associated with protection against clinical malaria. A phase 1 clinical …
which are significantly associated with protection against clinical malaria. A phase 1 clinical …
Naturally acquired antibodies to polymorphic and conserved epitopes of Plasmodium falciparum merozoite surface protein 3
Many studies on the role of merozoite surface protein 3 (MSP3) in immunity against malaria
have focused on a conserved section of MSP3. New evidence suggests that polymorphic …
have focused on a conserved section of MSP3. New evidence suggests that polymorphic …
Safety and immunogenicity of the Plasmodium falciparum merozoite surface protein-3 long synthethic peptide (MSP3-LSP) malaria vaccine in healthy, semi-immune …
SB Sirima, I Nébié, A Ouédraogo, AB Tiono, AT Konaté… - Vaccine, 2007 - Elsevier
The merozoite surface protein-3 long synthetic peptide (MSP3-LSP) comprises the amino
acid sequence 186–276 of the Plasmodium falciparum protein MSP3. It is currently in …
acid sequence 186–276 of the Plasmodium falciparum protein MSP3. It is currently in …
Potential impact of host immunity on malaria treatment outcome in Tanzanian children infected with Plasmodium falciparum
A Enevold, WMMM Nkya, M Theisen, LS Vestergaard… - Malaria journal, 2007 - Springer
Background In malaria endemic areas children may recover from malaria after
chemotherapy in spite of harbouring genotypically drug-resistant Plasmodium falciparum …
chemotherapy in spite of harbouring genotypically drug-resistant Plasmodium falciparum …
Differential regulation of IgG subclasses and IgE antimalarial antibody responses in complicated and uncomplicated Plasmodium falciparum malaria
P Tangteerawatana, SM Montgomery… - Parasite …, 2007 - Wiley Online Library
The aim of this study was to assess the immunoglobulin (Ig)‐subclass distribution of
antimalarial antibody responses in 110 and 169 Thai patients with complicated and …
antimalarial antibody responses in 110 and 169 Thai patients with complicated and …
Prevalence of plasmodium falciparum in active conflict areas of eastern Burma: a summary of cross-sectional data
AK Richards, L Smith, LC Mullany, CI Lee… - Conflict and Health, 2007 - Springer
Background Burma records the highest number of malaria deaths in southeast Asia and may
represent a reservoir of infection for its neighbors, but the burden of disease and magnitude …
represent a reservoir of infection for its neighbors, but the burden of disease and magnitude …