An emerging role for galectins in tuning the immune response: lessons from experimental models of inflammatory disease, autoimmunity and cancer

GA Rabinovich, FT Liu, M Hirashima… - Scandinavian journal …, 2007 - Wiley Online Library
Inflammation is a critical process for eliminating pathogens, but can lead to serious
deleterious effects if left unchecked. Identifying the endogenous factors that control immune …

The role of galectin-3 in cancer drug resistance

T Fukumori, H Kanayama, A Raz - Drug Resistance Updates, 2007 - Elsevier
The galectins comprise a family of 14 members of β-galactoside-binding proteins,
characterized by their affinity for β-galactosides and by a conserved sequence in the …

Tyrosol, the major extra virgin olive oil compound, restored intracellular antioxidant defences in spite of its weak antioxidative effectiveness

R Di Benedetto, R Varì, B Scazzocchio, C Filesi… - Nutrition, Metabolism …, 2007 - Elsevier
BACKGROUND AND AIM: Extra virgin olive oil has been associated with a reduced
incidence of risk factors for coronary heart disease also owing to the presence of antioxidant …

The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop

S Ramasamy, S Duraisamy, S Barbashov, T Kawano… - Molecular cell, 2007 - cell.com
The MUC1 heterodimeric transmembrane glycoprotein is aberrantly overexpressed by
diverse human carcinomas. Galectin-3 is a β-galactoside binding protein that has also been …

The role of galectin-3 in promotion of the inflammatory response.

FT Liu, DK Hsu - Drug news & perspectives, 2007 - europepmc.org
Galectin-3 is a member of a family of beta-galactoside-binding animal lectins and is distinct
from other members by the presence of tandem repeats in its N-terminal region. Like other …

Soluble galectin-3 is a strong, colonic epithelial-cell-derived, lamina propria fibroblast-stimulating factor

E Lippert, W Falk, F Bataille, T Kähne, M Naumann… - Gut, 2007 - gut.bmj.com
Background: Colonic lamina propria fibroblasts (CLPFs) play an important role in the
pathogenesis of fibrosis and strictures in Crohn's disease. Aim: To identify colonic epithelial …

Intestinal epithelial cell proteome in IL-10 deficient mice and IL-10 receptor reconstituted epithelial cells: impact on chronic inflammation

T Werner, A Shkoda, D Haller - Journal of proteome research, 2007 - ACS Publications
The interaction of nonpathogenic enteric bacteria with intestinal epithelial cells (IEC) in the
absence of host-derived Interleukin 10 (IL-10) may contribute to the development of chronic …

Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis

CL Bellac, RS Coimbra, F Simon, H Imboden… - Neurobiology of …, 2007 - Elsevier
Inflammation of the subarachnoid and ventricular space contributes to the development of
brain damage ie cortical necrosis and hippocampal apoptosis in pneumococcal meningitis …

Functional epithelial cell proteomics under conditions of chronic intestinal inflammation

A Shkoda - 2007 - mediatum.ub.tum.de
In this study we used IL-10 gene deficient mice monoassociated with Gram-positive
Enterococcus faecalis in order to characterize bacteria-epithelial interactions and host …

Mecanismos associados à perda de expressão do gene de galectina-3 em um modelo de progressão de melanoma murino

VR Teixeira - 2007 - teses.usp.br
Galectina-3 é uma lectina animal que apresenta afinidade por b-galactosídeos e que tem
sido associada à progressão tumoral e metástase. A expressão de galectina-3 encontra-se …