The ability to repair membrane damage is conserved across eukaryotic cells and is
necessary for the cells to survive a variety of physiological and pathological membrane …

Cell–cell fusion is a highly regulated and dramatic cellular event that is required for
development and homeostasis. Fusion may also play a role in the development of cancer …

The muscular dystrophies are a heterogeneous group of inherited disorders, defined by
progressive muscle weakness and atrophy. Following the discovery of dystrophin …

Using recombinant bead-conjugated emerin, we affinity-purified seven proteins from HeLa
cell nuclear lysates that bind emerin either directly or indirectly. These proteins were …

Dystrophic muscle disease can occur at any age. Early-or childhood-onset muscular
dystrophies may be associated with profound loss of muscle function, affecting ambulation …

Myoferlin and dysferlin are members of the ferlin family of membrane proteins. Recent
studies have shown that mutation or genetic disruption of myoferlin or dysferlin promotes …

Myoblast fusion follows a defined sequence of events that is strikingly similar in vertebrates
and invertebrates. Genetic analysis in Drosophila has identified many of the molecules that …

Previously, we reported that an isometric resistance training program that was effective in
stimulating muscle hypertrophy in ambulatory rats could not completely prevent muscle …

The dysferlin gene is mutated in limb‐girdle muscular dystrophy type 2B, Miyoshi myopathy,
and distal anterior compartment myopathy. In mature skeletal muscle, dysferlin is located …

Mutations that disrupt the dystrophin glycoprotein complex lead to plasma membrane
instability of cardiomyocytes and skeletal muscle myofibers. Instability of the plasma …