Chronic kidney disease: effects on the cardiovascular system

EL Schiffrin, ML Lipman, JFE Mann - Circulation, 2007 - Am Heart Assoc
Accelerated cardiovascular disease is a frequent complication of renal disease. Chronic
kidney disease promotes hypertension and dyslipidemia, which in turn can contribute to the …

Vascular calcification in patients with kidney disease: The vascular biology of calcification

RC Shroff, CM Shanahan - Seminars in dialysis, 2007 - Wiley Online Library
Vascular calcification is an active, cell‐mediated process that results from an imbalance
between the promoters and inhibitors of mineralization. The process of vascular calcification …

Progressive vascular calcification over 2 years is associated with arterial stiffening and increased mortality in patients with stages 4 and 5 chronic kidney disease

MK Sigrist, MW Taal, P Bungay… - Clinical Journal of the …, 2007 - journals.lww.com
Background and objectives: Vascular calcification is increasingly recognized as an
important component of cardiovascular disease in chronic kidney disease. The objective of …

Vascular calcification and osteoporosis—from clinical observation towards molecular understanding

LC Hofbauer, CC Brueck, CM Shanahan… - Osteoporosis …, 2007 - Springer
Patients with osteoporosis frequently suffer from vascular calcification, which was shown to
predict both cardiovascular morbidity/mortality and osteoporotic fractures. Various common …

Is the anti-inflammatory effect of regular exercise responsible for reduced cardiovascular disease?

KR Wilund - Clinical science, 2007 - portlandpress.com
Engaging in regular physical activity reduces the risk of developing CVD (cardiovascular
disease), but it is not certain to what degree this may be due to the anti-inflammatory effects …

[HTML][HTML] Association of serum fetuin-A levels with mortality in dialysis patients

MMH Hermans, V Brandenburg, M Ketteler… - Kidney international, 2007 - Elsevier
Calcifying atherosclerosis is an active process, which is controlled by calcification inhibitors
and inducers. Fetuin-A, an acute phase glycoprotein, is one of the more powerful circulating …

Association of fetuin-A with mitral annular calcification and aortic stenosis among persons with coronary heart disease: data from the Heart and Soul Study

JH Ix, GM Chertow, MG Shlipak, VM Brandenburg… - Circulation, 2007 - Am Heart Assoc
Background—Fetuin-A is a multifunctional hepatic secretory protein that inhibits dystrophic
vascular and valvular calcification. Lower serum fetuin-A concentrations are associated with …

Calcification of coronary intima and media: immunohistochemistry, backscatter imaging, and x-ray analysis in renal and nonrenal patients

ML Gross, HP Meyer, H Ziebart, P Rieger… - Clinical Journal of the …, 2007 - journals.lww.com
Coronary calcification is a potent predictor of cardiac events. In patients with chronic renal
disease, both prevalence and intensity of coronary calcification are increased. It has …

Vascular calcification and arterial stiffness in chronic kidney disease: implications and management

ND Toussaint, PG Kerr - Nephrology, 2007 - Wiley Online Library
Cardiovascular (CV) disease is the commonest cause of mortality in patients with chronic
kidney disease (CKD). Vascular calcification (VC), induced by calcium and phosphate …

Structural dynamics of a colloidal protein-mineral complex bestowing on calcium phosphate a high solubility in biological fluids

A Heiss, W Jahnen-Dechent, H Endo, D Schwahn - Biointerphases, 2007 - pubs.aip.org
The concentration of mineral solutes in mammalian blood is considerably higher than that
predicted by their solubility product. The plasma protein fetuin-A inhibits calcium phosphate …