Insulin signaling and glucose transport in insulin resistant human skeletal muscle

HKR Karlsson, JR Zierath - Cell biochemistry and biophysics, 2007 - Springer
Insulin increases glucose uptake and metabolism in skeletal muscle by signal transduction
via protein phosphorylation cascades. Insulin action on signal transduction is impaired in …

Corticosterone impairs insulin-stimulated translocation of GLUT4 in the rat hippocampus

GG Piroli, CA Grillo, LR Reznikov, S Adams… - …, 2007 - karger.com
Background: Exposure to stress levels of glucocorticoids produces physiological responses
that are characteristic of type 2 diabetes, such as peripheral insulin resistance and …

Functional Studies of Akt Isoform Specificity in Skeletal Muscle in Vivo; Maintained Insulin Sensitivity Despite Reduced Insulin Receptor Substrate-1 Expression

ME Cleasby, TA Reinten, GJ Cooney… - Molecular …, 2007 - academic.oup.com
The phosphoinositide 3-kinase/Akt pathway is thought to be essential for normal insulin
action and glucose metabolism in skeletal muscle and has been shown to be dysregulated …

[HTML][HTML] In-depth analysis of the adipocyte proteome by mass spectrometry and bioinformatics

J Adachi, C Kumar, Y Zhang, M Mann - Molecular & Cellular Proteomics, 2007 - ASBMB
Adipocytes are central players in energy metabolism and the obesity epidemic, yet their
protein composition remains largely unexplored. We investigated the adipocyte proteome by …

[HTML][HTML] VDAC1 serves as a mitochondrial binding site for hexokinase in oxidative muscles

K Anflous-Pharayra, ZJ Cai, WJ Craigen - Biochimica et Biophysica Acta …, 2007 - Elsevier
Voltage-dependent anion channels (VDACs), also known as mitochondrial porins, are the
main pathway for metabolites across the mitochondrial outer membrane and may serve as …

Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart

EJ Miller, J Li, KM Sinusas… - American Journal of …, 2007 - journals.physiology.org
Glucose uptake in the heart is mediated by specific glucose transporters (GLUTs) present on
cardiomyocyte cell surface membranes. Metabolic stress and insulin both increase glucose …

Involvement of RelA-associated inhibitor in regulation of trophoblast differentiation via interaction with transcriptional factor specificity protein-1

R Minekawa, M Sakata, Y Okamoto, M Hayashi… - …, 2007 - academic.oup.com
Glucose transporter-1 (GLUT1), one of the key functional indicators of placental
differentiation, has an important role in placental glucose transport. We previously showed …

[PDF][PDF] Fibre type dependent expression of glucose transporters in human skeletal musclesUgeskr Læger 2007; 169 (16): 1476

LM Gaster, TW Teasdale - UGESKR LÆGER, 2007 - content.ugeskriftet.dk
TEGN EN ERHVERVSANSVARSFORSIKRING! Page 1 UGESKR LÆGER 169/16 | 16. APRIL
2007 1476 VIDENSKAB OG PRAKSIS | AKADEMISKE AFHANDLINGER > AKADEMISKE …

[图书][B] Role of Wnt signaling and glycogen synthase kinase-3 beta in adipocyte biology

DA Silva - 2007 - search.proquest.com
Adipocyte differentiation from fibroblasts into fat cells (adipogenesis) is regulated by two
families of transcription factors: CCAAT/enhancer binding proteins (C/EBPs), members of the …

[PDF][PDF] La régulation du métabolisme du glucose par la protéine tyrosine phosphatase SHP-1

S Bergeron - 2007 - Citeseer
Résumé Lorsque l'insuline se lie à son récepteur, elle induit une cascade de réactions
indispensables à l'utilisation du glucose. La résistance à l'insuline et le diabète de type 2 qui …