Bronchoalveolar lavage (BAL) has been used widely in the diagnosis of infection. More than
30 years after its description, its use in the clinical management of interstitial lung disease …

Rationale: The Scleroderma Lung Study enrolled 158 patients with scleroderma-related
interstitial lung disease in a placebo-controlled trial of oral cyclophosphamide (CYC) …

OBJECTIVE: An important barrier in the study of systemic sclerosis (SSc) is the difficulty in
measuring disease activity. We reviewed the literature on currently available global …

More effective therapeutic strategies are required for patients with poor-prognosis systemic
sclerosis (SSc). A phase 2 single-arm study of high-dose immunosuppressive therapy …

Objective To explore the relationship between changes in the severity of skin disease and
morbidity and mortality in patients with diffuse cutaneous systemic sclerosis (dcSSc) …

Objective To evaluate the prognostic value of bronchoalveolar lavage (BAL) cellular profiles
in patients with systemic sclerosis–associated interstitial lung disease (SSc‐ILD). Methods …

Objectives. A clinico-pathological study in diffuse systemic sclerosis (SSc) patients was
performed to analyse whether the skin histological organization and the pro-fibrotic signals …

Joint analysis of longitudinal measurements and survival data has received much attention
in recent years. However, previous work has primarily focused on a single failure type for the …

Background: The 6-min walk test (6MWT) is increasingly used as an outcome measure in
interstitial lung disease (ILD). Aim: To evaluate the usefulness of the 6MWT in a cohort of …

Objectives: Pulmonary fibrosis is a leading cause of death in systemic sclerosis (SSc). This
report examines the differences at baseline and over 12 months between patients with …