The lens circulation

RT Mathias, J Kistler, P Donaldson - Journal of Membrane Biology, 2007 - Springer
The lens is the largest organ in the body that lacks a vasculature. The reason is simple:
blood vessels scatter and absorb light while the physiological role of the lens is to be …

[HTML][HTML] Refractive defects and cataracts in mice lacking lens intrinsic membrane protein-2

A Shiels, JM King, DS Mackay… - … ophthalmology & visual …, 2007 - arvojournals.org
purpose. To characterize the optical properties of lenses from mice deficient in the gene for
lens intrinsic membrane protein-2 (Lim2), which encodes the second most abundant integral …

Functional expression of aquaporins in embryonic, postnatal, and adult mouse lenses

K Varadaraj, SS Kumari… - … dynamics: an official …, 2007 - Wiley Online Library
Abstract Aquaporin 0 (AQP0) and AQP1 are expressed in the lens, each in a different cell
type, and their functional roles are not thoroughly understood. Our previous study showed …

[HTML][HTML] Age-related cataracts in α3Cx46-knockout mice are dependent on a calpain 3 isoform

Y Tang, X Liu, RK Zoltoski, LA Novak… - … & visual science, 2007 - arvojournals.org
purpose. Previous studies have demonstrated that in 129α3Cx46−/− mice, age-related
nuclear cataract is formed. In the present study, a more in vivo-relevant model was …

Transgenic overexpression of connexin50 induces cataracts

J Chung, VM Berthoud, L Novak, R Zoltoski… - Experimental eye …, 2007 - Elsevier
To examine the effects of increased expression of Cx50 in the mouse lens, transgenic mice
were generated using a DNA construct containing the human Cx50 coding region and a C …

Localization of aquaporin-0 immunoreactivity in the rat retina

I Iandiev, T Pannicke, W Härtig, J Grosche… - Neuroscience …, 2007 - Elsevier
Previous RT-PCR experiments revealed the expression of gene transcripts for a variety of
aquaporins in the neural retina, including aquaporin-0. We investigated by …

水通道蛋白在大鼠氧化性白内障晶状体上的表达

张虹, 张金玲 - 华中科技大学学报: 医学版, 2007 - cqvip.com
目的观察Ⅰ 型水通道蛋白(AQP1) 在正常及氧化性白内障模型大鼠晶状体上的表达,
探讨其在氧化性白内障发生过程中的作用. 方法将健康清洁级Wistar 大鼠60 …

Overview of Genetic Disorders

JL Wiggs - Garner and Klintworth's Pathobiology of Ocular …, 2007 - taylorfrancis.com
Deoxyribonucleic acid is the molecule that stores the complex genetic information necessary
for normal growth, development, and cell function, and is the site for the mutations …