Retinoic acid and the heart
J Pan, KM Baker - Vitamins & Hormones, 2007 - Elsevier
Retinoic acid (RA), the active derivative of vitamin A, by acting through retinoid receptors, is
involved in signal transduction pathways regulating embryonic development, tissue …
involved in signal transduction pathways regulating embryonic development, tissue …
Sodium tanshinone IIA sulfonate depresses angiotensin II-induced cardiomyocyte hypertrophy through MEK/ERK pathway
L Yang, X Zou, Q Liang, H Chen, J Feng… - … & molecular medicine, 2007 - nature.com
Cardiomyocyte hypertrophy is a major cause of morbidity and mortality worldwide. The aim
of this study is to determine the effects of sodium tanshinone IIA sulfonate (STS) on …
of this study is to determine the effects of sodium tanshinone IIA sulfonate (STS) on …
Aldosterone induces circadian gene expression of clock genes in H9c2 cardiomyoblasts
K Tanaka, N Ashizawa, H Kawano, O Sato, S Seto… - Heart and vessels, 2007 - Springer
We examined mRNA expression of the clock genes (Per1, Per2, and Bmal1) and PAI-1
(plasminogen activator inhibitor-1) after aldosterone treatment every 4 h up to 48 h in H9c2 …
(plasminogen activator inhibitor-1) after aldosterone treatment every 4 h up to 48 h in H9c2 …
Involvement of insulin-regulated aminopeptidase and/or aminopeptidase N in the angiotensin IV-induced effect on dopamine release in the striatum of the rat
B Stragier, H Demaegdt, D De Bundel, I Smolders… - Brain research, 2007 - Elsevier
Locally administered angiotensin IV causes a dose-dependent increase of the dopamine
levels in the striatum of the rat. The aminopeptidases insulin-regulated aminopeptidase …
levels in the striatum of the rat. The aminopeptidases insulin-regulated aminopeptidase …
Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine
C Rugale, S Delbosc, A Mimran… - Journal of cardiovascular …, 2007 - journals.lww.com
The ability of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor simvastatin to reverse
established cardiovascular and renal alterations and oxidative stress was assessed in …
established cardiovascular and renal alterations and oxidative stress was assessed in …
The role and regulation of cardiac angiotensin-converting enzyme for noninvasive molecular imaging in heart failure
O Aras, SA Messina, J Shirani, WC Eckelman… - Current Cardiology …, 2007 - Springer
Congestive heart failure is a pathologic condition characterized by progressive decrease in
left ventricular contractility and consequent decline of cardiac output. There is convincing …
left ventricular contractility and consequent decline of cardiac output. There is convincing …
Angiotensin Receptor Blockers in Chronic Heart Failure: Clinical Implications and Molecular Mechanisms
Angiotensin II is the main effector molecule of the renin-angiotensin system and has been
implicated in regulating cell growth, inflammation and fibrosis, contributing to cardiac …
implicated in regulating cell growth, inflammation and fibrosis, contributing to cardiac …
Angiotensin IV Binding Site: The AT4 Receptor or Insulin-Regulated Aminopeptidase
Abstract Angiotensin IV (Ang IV) is a hexapeptide fragment corresponding to amino acids 3–
8 (VYIHPF) of angiotensin II (Ang II) that is formed by consecutive actions of aminopeptidase …
8 (VYIHPF) of angiotensin II (Ang II) that is formed by consecutive actions of aminopeptidase …