Relatively little is known about immune evasion during the productive phase of infection by
the γ1-herpesvirus Epstein–Barr virus (EBV). The use of a unique system to isolate cells in …

Biologically active proteins without stable ordered structure (ie, intrinsically disordered
proteins) are attracting increased attention. Functional repertoires of ordered and disordered …

In the human genome, the five adenosine triphosphate (ATP)-binding cassette (ABC) half
transporters ABCB2 (TAP1), ABCB3 (TAP2), ABCB9 (TAP-like), and in part, also ABCB8 and …

The present invention is directed to universal T cells and their use in treating diseases and
other physiological condi tions. More speci? cally, the present invention is directed to …

Amplicons are defective and non-integrative vectors derived from herpes simplex virus type
1. They carry no virus genes in the vector genome and are, therefore, not toxic to the infected …

Mature dendritic cells (DCs) are the most potent antigen-presenting cells within the human
immune system. However, Herpes simplex virus type 1 (HSV-1) is able to interfere with DC …

Like all other members of the herpesvirus family, the closely related human herpesviruses-6
and-7 (HHV-6, 7) persist in their host throughout life. In so doing, without exception, every …

Herpes simplex virus type 1 (HSV‐1) causes lifelong latent infections in most humans.
Periodical virus reactivations from latency in the neurons of sensitive ganglia lead to …

Herpes simplex virus (HSV) recombinants induce durable immune responses in rhesus
macaques and mice and have induced partial protection in rhesus macaques against …

The use of oncolytic herpes simplex virus type 1 (HSV-1) is a promising strategy for cancer
treatment. Accumulating evidence indicates that, aside from the extent of replication …