Protein engineering holds great promise for the development of new biosensors,
diagnostics, therapeutics, and agents for bioremediation. Despite some remarkable …

Menaquinone is an electron carrier in the respiratory chain of Escherichia coli during
anaerobic growth. Its biosynthesis involves (1 R, 6 R)-2-succinyl-6-hydroxy-2, 4 …

The protein databases contain many proteins with unknown function. A computational
approach for predicting ligand specificity that requires only the sequence of the unknown …

The catalytic promiscuity of E. coli alkaline phosphatase (AP) and many other enzymes
provides a unique opportunity to dissect the origin of enzymatic rate enhancements via a …

Enzyme catalysis reflects a dynamic interplay between charged and polar active site
residues that facilitate function, stabilize transition states, and maintain overall protein …

The turnover product of the committed step of menaquinone biosynthesis was isolated and
determined to be (1 R, 2 S, 5 S, 6 S)-2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 …

Vitamin K2, or menaquinone, is an essential cofactor for many organisms and the enzymes
involved in its biosynthesis are potential antimicrobial drug targets. One of these enzymes, 1 …

The use of remote sensing technology has made it possible for the non-contact
measurement of soil moisture content (SMC). Many remote sensing techniques can be used …

MosA is a protein found in Sinorhizobium meliloti L5-30 and has been suggested to be
responsible for the biosynthesis of the rhizopine 3-O-methyl-scyllo-inosamine (3-MSI) from …

Enzymatic Specificity Enzymes are expected to be specific, though cases have been
identified of enzymes promiscuously catalyzing reactions in addition to their native one …