Tertiary lymphoid structures in the pancreas promote selection of B lymphocytes in autoimmune diabetes
PL Kendall, G Yu, EJ Woodward… - The Journal of …, 2007 - journals.aai.org
Autoimmune diabetes occurs when invading lymphocytes destroy insulin-producing β cells
in pancreatic islets. The role of lymphocytic aggregates at this inflammatory site is not …
in pancreatic islets. The role of lymphocytic aggregates at this inflammatory site is not …
B cell depletion: a novel therapy for autoimmune diabetes?
H Bour-Jordan, JA Bluestone - The Journal of clinical …, 2007 - Am Soc Clin Investig
Autoimmune diabetes is believed to be mediated primarily by T cells. However, B cells have
been implicated in the pathogenesis of the disease in NOD mice. Although preclinical …
been implicated in the pathogenesis of the disease in NOD mice. Although preclinical …
Constitutive expression of B7-1 on B cells uncovers autoimmunity toward the B cell compartment in the nonobese diabetic mouse
H Bour-Jordan, BL Salomon, HL Thompson… - The Journal of …, 2007 - journals.aai.org
The NOD mouse is an invaluable model for the study of autoimmune diabetes. Furthermore,
although less appreciated, NOD mice are susceptible to other autoimmune diseases that …
although less appreciated, NOD mice are susceptible to other autoimmune diseases that …
Cellular expression requirements for inhibition of type 1 diabetes by a dominantly protective major histocompatibility complex haplotype
YG Chen, PA Silveira, MA Osborne, HD Chapman… - Diabetes, 2007 - Am Diabetes Assoc
The H2 g7 (Kd, Ag7, Enull, and Db) major histocompatibility complex (MHC) is the primary
genetic contributor to type 1 diabetes in NOD mice. NOD stocks congenically expressing …
genetic contributor to type 1 diabetes in NOD mice. NOD stocks congenically expressing …
[PDF][PDF] Invasion of the killer B's in type 1 diabetes
Introduction 3. An important role for B cells in T1D 4. What is the role of B cells in T1D? 4.1. B
cells function as a diabetogenic APC 4.2. Specific Ig-mediated antigen capture allows B …
cells function as a diabetogenic APC 4.2. Specific Ig-mediated antigen capture allows B …
[图书][B] Genetics and functions of innate-like lymphocyte subsets
J Rolf - 2007 - gupea.ub.gu.se
The immune system contains three different branches: innate immunity, adaptive immunity
and innate-like lymphocytes that share properties both with the innate and adaptive immune …
and innate-like lymphocytes that share properties both with the innate and adaptive immune …
Морфологічні зміни лімфоїдних структур селезінки в постнатальному онтогенезі в нормі та при антигенній стимуляції
АО Гербут - 2007 - repository.tdmu.edu.ua
Дисертація містить дані про величину відносних площ і щільності імунокомпетентних
клітин структурних компонентів білої пульпи селезінки: лімфоїдних вузликів та їх …
клітин структурних компонентів білої пульпи селезінки: лімфоїдних вузликів та їх …
[图书][B] A unique memory B cell subset correlates with adverse outcomes in human SLE
MW Nicholas - 2007 - search.proquest.com
Systemic lupus erythematosus (SLE) is a devastating systemic autoimmune disease marked
by the production of antinuclear autoantibodies whose etiology has both genetic and …
by the production of antinuclear autoantibodies whose etiology has both genetic and …
[PDF][PDF] The role of nuclear factor-kappa B in beta-cell survival and function
D Liuwantara - 2007 - unsworks.unsw.edu.au
In Type 1 diabetes, beta-cells is subjected to an autoimmune-mediated apoptotic and
inflammatory attack. Whilst lymphocytes are the primary contributor of beta-cell death …
inflammatory attack. Whilst lymphocytes are the primary contributor of beta-cell death …
Mechanisms of anti-Sm B cell activation in autoimmune Fas-deficient mice
KL Conway - 2007 - search.proquest.com
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the
production of anti-nuclear autoantibodies to Smith (Sm), a component of a ribonucleoprotein …
production of anti-nuclear autoantibodies to Smith (Sm), a component of a ribonucleoprotein …