Adequate intakes of vitamins and trace elements are required for the immune system to
function efficiently. Micronutrient deficiency suppresses immune functions by affecting the …

Adequate intakes of micronutrients are required for the immune system to function efficiently.
Micronutrient deficiency suppresses immunity by affecting innate, T cell mediated and …

Currently available evidence from epidemiologic, animal, and intervention studies does not
unequivocally support the role of folate, a water‐soluble B vitamin and important cofactor in …

Nationwide fortification of enriched uncooked cereal grains with folic acid began in the
United States and Canada in 1996 and 1997, respectively, and became mandatory in 1998 …

Background: Monitoring the folate status of US population groups over time has been a
public health priority for the past 2 decades, and the focus has been enhanced since the …

In a recent study of older participants (age≥ 60 years) in the 1999–2002 National Health
and Nutrition Examination Survey (NHANES), we showed that a combination of high serum …

Following an introduction of the importance of folates and the rationale for seeking to
estimate fractional folate absorption from foods (especially for countries not having a …

Neural tube defects (NTDs) refer to a cluster of neurodevelopmental conditions associated
with failure of neural tube closure during embryonic development. Worldwide prevalence of …

Background All flour in the USA is fortified with folic acid at a level of 140 μg/100 g which is
estimated to supply an extra 100 μg daily to the average diet. Some researchers have …

Background: Folic aid plays an essential role in cellular metabolism. Its deficiency can lead
to neural tube defects. However, optimization of body folate homeostasis can reduce the …