High-affinity iron acquisition is mediated by siderophore-dependent pathways in the majority
of pathogenic and nonpathogenic bacteria and fungi. Considerable progress has been …

For nearly 20 years, it was believed that Legionella pneumophila does not produce
siderophores. Yet, we have now determined that L. pneumophila secretes a siderophore …

The virulence of Legionella pneumophila is dependent upon its capacity to acquire iron. To
identify genes involved in expression of its siderophore, we screened a mutagenized …

The asbABCDEF gene cluster from Bacillus anthracis is responsible for biosynthesis of
petrobactin, a catecholate siderophore that functions in both iron acquisition and virulence in …

Oligomerization and macrocyclization reactions are key steps in the biosynthesis of many
bioactive natural products. Important macrocycles include the antibiotic daptomycin (1; ref.) …

Streptomyces coelicolor and Streptomyces pilosus produce desferrioxamine siderophores
which are encoded by the desABCD gene cluster. S. pilosus is used for the production of …

Recently, iron acquisition and, more specifically, enzymes involved in siderophore
biosynthesis have become attractive targets for discovery of new antibiotics. Accordingly …

Petrobactin is an iron-chelating siderophore originally isolated from Marinobacter
hydrocarbonoclasticus that has been shown to play an important role in growth under iron …

Bordetella pertussis, Bordetella parapertussis, and Bordetella bronchiseptica are pathogens
with a complex iron starvation stress response important for adaptation to nutrient limitation …

In fish pathogen Vibrio alginolyticus MVP01, the isolated 11-gene cluster consisted of two
divergently transcribed, Fe 3+ and ferric uptake regulator (Fur) regulated operons …