Exacerbations of chronic obstructive pulmonary disease (COPD) are episodes of worsening
of symptoms, leading to substantial morbidity and mortality. COPD exacerbations are …

Exacerbations of chronic obstructive pulmonary disease are of major importance in terms of
their prolonged detrimental effects on patients, the acceleration in disease progression and …

Background Depressive symptoms are common among patients with chronic obstructive
pulmonary disease (COPD), but depression's impact on COPD outcomes has not been fully …

Background Severe Acute Respiratory Syndrome (SARS) became a global epidemic in
2003. Comprehensive information on 1-year outcomes and health care utilization is lacking …

Evidence suggests that eosinophilic airway inflammation is important in the pathogenesis of
severe chronic obstructive pulmonary disease (COPD) exacerbations. The present authors …

Chronic obstructive pulmonary disease (COPD) exacerbations are associated with
increased airway and systemic inflammation, though relationships between exacerbation …

Chronic obstructive pulmonary disease (COPD) is a major respiratory illness in Canada that
is both preventable and treatable. Our understanding of the pathophysiology of this complex …

Background Patients who survive a severe exacerbation of COPD are at high risk of
rehospitalization for COPD and death. The objective of this study was to determine …

Rationale: Exacerbations of chronic obstructive pulmonary disease (COPD) greatly
contribute to declining health status and the progression of the disease, thereby incurring …

Background: Frequent exacerbations are associated with a faster decline in FEV 1, impaired
health status, and worse survival. Their impact and temporal relationship with other …