Pulmonary arterial hypertension of variable degree is commonly associated with adult
congenital heart disease. Depending on size and location of the underlying cardiac defect …

Idiopathic pulmonary fibrosis (IPF) is an untreatable diffuse parenchymal lung disease with a
median survival of< 3 years. Pulmonary hypertension (PH) is frequently seen in patients with …

Pulmonary hypertension (PH) may complicate idiopathic pulmonary fibrosis (IPF) but the
prevalence of PH in IPF remains undefined. The present authors sought to describe the …

The complex nature of interactions between the pulmonary and cardiovascular systems is
becoming increasingly appreciated. Pulmonary vascular abnormalities are frequently …

Pulmonary hypertension is a common finding in patients with idiopathic pulmonary fibrosis
(IPF), and is associated with increased morbidity and mortality. Therapy with sildenafil has …

BACKGROUND: Various innovative pharmacologic strategies for the treatment of patients
with pulmonary hypertension have been tested in recent years. Neither their comparative …

Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and a course that is unpredictable.
Pulmonary hypertension may complicate the course of IPF and potentially impact prognosis …

Background: Pulmonary hypertension (PH) is a disease condition characterized by
abnormally increased pulmonary artery pressures and often is associated with a poor …

Background—Pulmonary arterial hypertension (PAH) is a life-threatening disease,
characterized by vascular smooth muscle cell hyperproliferation. The calcium/calmodulin …

Hypoxia and endothelial dysfunction play a central role in the development of pulmonary
hypertension. Cor pulmonale is a maladaptive response to pulmonary hypertension. The …