Objective To reevaluate the efficacy and safety of adjunctive low‐dose methotrexate (MTX)
in giant cell arteritis (GCA). Methods An individual patient data meta‐analysis of 3 …

Background The choice of antiepileptic drug for an individual should be based upon the
highest quality evidence regarding potential benefits and harms of the available treatments …

Migraine is often associated with health consequences including impaired quality of life, and
the cost of treating migraine headaches places a significant financial burden on patients …

Medicine and evidence: knowledge and action in clinical practice Medicine and evidence:
knowledge and action in clinical practice J Eval Clin Pract. 2007 Aug;13(4):481-503. doi …

Background Alternative methods for individual patient data (IPD) meta-analysis of time-to-
event outcomes have been established and utilized in practice. The most common approach …

A systematic review is performed in attempt to answer a specific research question by
means of objective, unbiased evaluation of all pertinent available evidence. Component …

Systematic Reviews gain more and more importance in evidence-based-practice. So far the
most developed review methods are on quantitative research. There are some publications …

Systematische Reviews haben eine hohe Bedeutung für eine evidenz-basierte Gesundheits-
und Pflegeversorgung. Bislang sind systematische Verfahren für das Erstellen von …

Real-world experiments in which some experimental units (eg, people or roadway sites or
vehicles) are randomized to treatment and others to no treatment are increasingly regarded …

The 2000 Institute of Medicine (IOM) report “To Err is Human” identified hospitals to be
unsafe environments. Medical errors are rampant. 1–3 By conservative estimates, these …