A key issue in the treatment of many cancers is the development of resistance to
chemotherapeutic drugs. Resistance mechanisms are numerous and complex. One of them …

It is firmly established that interferon-γ (IFN-γ) plays a mandatory role in acquired protective
immunity to pathogenic mycobacteria and other intracellular pathogens. Therefore, it seems …

Abstract Purpose: The Janus-activated kinase/signal transducers and activators of
transcription (STAT) pathway of IFN signaling is important to immunoregulation and tumor …

This work expands our tissue proteome capabilities from the analysis of soluble proteins in
previous studies to the examination of membrane proteins within the pellets of enriched and …

Antigen peptides are actively transported across the endoplasmic reticulum by the
transporters associated with antigen presentation (TAP). TAP genes polymorphism could …

MRP1 couples ATP binding/hydrolysis to solute transport. We have shown that ATP binding
to nucleotide-binding-domain 1 (NBD1) plays a regulatory role whereas ATP hydrolysis at …

Many malignant cancer cells downregulate human leukocyte antigen (HLA) class I antigen
expression to evade T cell recognition. However, hepatocellular carcinoma (HCC) is …

Summary Background. Condyloma acuminatum (CA), caused by human papillomavirus
(HPV), is characterized by a variable clinical course that can include significant morbidity …

There is an urgent need for the development of technologies that allow the monitoring of
protein expression and processing in tumor tissues resulting from development, physiology …

Abstract Purpose: The Janus-activated kinase/signal transducers and activators of
transcription (STAT) pathway of IFN signaling is important to immunoregulation and tumor …