Molecular epidemiology of malaria
DJ Conway - Clinical Microbiology Reviews, 2007 - Am Soc Microbiol
Malaria persists as an undiminished global problem, but the resources available to address
it have increased. Many tools for understanding its biology and epidemiology are well …
it have increased. Many tools for understanding its biology and epidemiology are well …
[HTML][HTML] Long-term clinical protection from falciparum malaria is strongly associated with IgG3 antibodies to merozoite surface protein 3
C Roussilhon, C Oeuvray, C Müller-Graf, A Tall… - PLoS …, 2007 - journals.plos.org
Background Surrogate markers of protective immunity to malaria in humans are needed to
rationalize malaria vaccine discovery and development. In an effort to identify such markers …
rationalize malaria vaccine discovery and development. In an effort to identify such markers …
[HTML][HTML] Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome
J Mu, P Awadalla, J Duan, KM McGee, J Keebler… - Nature …, 2007 - nature.com
One goal in sequencing the Plasmodium falciparum genome, the agent of the most lethal
form of malaria, is to discover vaccine and drug targets. However, identifying those targets in …
form of malaria, is to discover vaccine and drug targets. However, identifying those targets in …
Vaccines against malaria–an update
K Matuschewski, AK Mueller - The FEBS journal, 2007 - Wiley Online Library
Malaria vaccine discovery and development follow two principal strategies. Most subunit
vaccines are designed to mimic naturally acquired immunity that develops over years upon …
vaccines are designed to mimic naturally acquired immunity that develops over years upon …
Plasmodium falciparum Merozoite Surface Protein 3 Is a Target of Allele-Specific Immunity and Alleles Are Maintained by Natural Selection
SD Polley, KKA Tetteh, JM Lloyd… - The Journal of …, 2007 - academic.oup.com
Background Plasmodium falciparum merozoite surface protein (MSP) 3 is an asexual blood-
stage malaria vaccine candidate antigen. Sequence polymorphisms divide alleles into 2 …
stage malaria vaccine candidate antigen. Sequence polymorphisms divide alleles into 2 …
[HTML][HTML] Dynamics of polymorphism in a malaria vaccine antigen at a vaccine-testing site in Mali
SL Takala, D Coulibaly, MA Thera, A Dicko… - PLoS …, 2007 - journals.plos.org
Background Malaria vaccines based on the 19-kDa region of merozoite surface protein 1
(MSP-119) derived from the 3D7 strain of Plasmodium falciparum are being tested in clinical …
(MSP-119) derived from the 3D7 strain of Plasmodium falciparum are being tested in clinical …
Genetic Diversity and Selection at the Plasmodium vivax Apical Membrane Antigen-1 (PvAMA-1) Locus in a Sri Lankan Population
AM Gunasekera, T Wickramarachchi… - Molecular biology …, 2007 - academic.oup.com
Plasmodium vivax apical membrane antigen 1 (PvAMA-1) is an important malaria vaccine
candidate. We present the first comprehensive analysis of nucleotide diversity across the …
candidate. We present the first comprehensive analysis of nucleotide diversity across the …
Plasmodium falciparum genetic diversity in western Kenya highlands
The present study examined the genetic diversity and population structure of Plasmodium
falciparum in western Kenya by analyzing the polymorphism of 12 microsatellite loci and two …
falciparum in western Kenya by analyzing the polymorphism of 12 microsatellite loci and two …
A comparative study of the genetic diversity of the 42 kDa fragment of the merozoite surface protein 1 in Plasmodium falciparum and P. vivax
MA Pacheco, AC Poe, WE Collins, AA Lal… - Infection, Genetics and …, 2007 - Elsevier
We investigated the genetic diversity of the 42kDa fragment of the merozoite surface protein
1 (MSP-1) antigen in Plasmodium falciparum and P. vivax, as well as in non-human primate …
1 (MSP-1) antigen in Plasmodium falciparum and P. vivax, as well as in non-human primate …
Antigenic Polymorphism and Naturally Acquired Antibodies to Plasmodium vivax Merozoite Surface Protein 1 in Rural Amazonians
MS Bastos, M da Silva-Nunes… - Clinical and Vaccine …, 2007 - Am Soc Microbiol
Merozoite surface protein 1 of Plasmodium vivax (PvMSP-1), a major target for malaria
vaccine development, contains six highly polymorphic domains interspersed with conserved …
vaccine development, contains six highly polymorphic domains interspersed with conserved …