A unique class of duocarmycin and CC-1065 analogues subject to reductive activation

W Jin, JD Trzupek, TJ Rayl, MA Broward… - Journal of the …, 2007 - ACS Publications
N-Acyl O-amino phenol derivatives of CBI-TMI and CBI-indole2 are reported as prototypical
members of a new class of reductively activated prodrugs of the duocarmycin and CC-1065 …