Among the different families of transmembrane receptors, G-proteincoupled receptors
(GPCR) form the largest superfamily being present in yeast, plants, protozoa and metazoa …

Finnish alcoholic, impulsive, habitually violent offenders have been found to have low brain
serotonin (5‐hydroxytryptamine; 5‐HT) turnover which is associated with impaired impulse …

Abstract The serotonin 2C (HTR2C) and 1A (HTR1A) receptors have been involved in
suicide‐related behaviors. We studied gene variants of both receptors in suicide attempters …

Rationale Perphenazine, a classical antipsychotic drug, has the potential to induce
extrapyramidal side effects (EPS). Dopaminergic and serotonergic pathways are involved in …

Recent work on the molecular genetics of complex traits in typical and atypical human
development has focused primarilyon associations of single genes with behavior. Disparate …

A central dogma of G protein-coupled receptor (GPCR) pharmacology has been the concept
that unlike agonists, antagonist ligands display equivalent affinities for a given receptor …

Contents EI Christensen and R. Nielsen: Role of Megalin and Cubilin in Renal Physiology
and Pathophysiology G. Zifarelli and M. Pusch: CLC Chloride Channels and Transporters: A …

Background Altered serotonergic function is implicated in the aetiology and pathogenesis of
a host of psychiatric disorders, and structural variations/polymorphisms in genes encoding …

Antisocial behaviour is both heterogeneous and the product of interacting genetic and
environmental factors acting at different levels of causation. Heritability studies show that …

The objectives of this study were to determine if the HTR2C Cys23Ser polymorphism is
associated with migraine in a case-control study, and to perform a meta-analysis with …