Targeted biologic therapies have revolutionised treatment of immune-mediated
inflammatory diseases (IMIDs) due to their efficacy, speed of onset and tolerability. The …

Murine mesenchymal stem cells (MSC) have the ability to inhibit allogeneic immune
responses. Two different mechanisms, either cell contact-dependent or independent, have …

Background: Juvenile idiopathic arthritis (JIA) consists of a heterogeneous group of
disorders with, for the most part, an unknown immunopathogenesis. Although onset and …

IL-17 and its receptor are founding members of a novel family of inflammatory cytokines. IL-
17 plays a pathogenic role in rheumatoid arthritis (RA)–associated bone destruction …

Objectives: To identify peripheral blood autoantibody and cytokine profiles that characterise
clinically relevant subgroups of patients with early rheumatoid arthritis using arthritis antigen …

Infectious diseases are still the number one killer of human beings. Even in developed
countries, infectious diseases continue to be a major health threat. This article explores a …

Drug-induced hepatitis remains a challenging problem for drug development and safety
because of the lack of animal models. In the current work, we discovered a unique …

Inflammation has been recently implicated in pathogenesis of dementia disorders. Effect of
anti-dementia (Acetylcholinesterase inhibitor) drugs tacrine, rivastigmine and donepezil …

Prodigiosin was isolated from marine bacteria Hahella chejuensis which has been recently
discovered from Marado, Cheju Island, Republic of Korea. Immunosuppressive properties …

Chinese herbs are useful edible and medicinal plants for their immune modulatory functions.
We have proven that (S)-armepavine (C19H23O3N; MW313) from Nelumbo nucifera inhibits …