Progress in management of critically ill neurological patients has led to improved survival
rates. However, severe residual neurological impairment, such as persistent coma, occurs in …

Neurodegenerative diseases of the central nervous system are often associated with
impaired learning and memory, eventually leading to dementia. An important aspect in pre …

Delirium, stupor and coma are common clinical states that confront clinicians in almost every
medical specialty. With appropriate diagnosis and treatment, coma can often be treated …

Traumatic axonal injury (TAI) may contribute greatly to neurological impairments after
traumatic brain injury, but it is difficult to assess with conventional imaging. We quantitatively …

CT and MRI are now the imaging techniques for acute and subacute brain injury,
respectively. Diffusion tensor imaging is being developed to provide more information on …

Our ability to map and intervene in the structure of the human brain is proceeding at a very
quick rate. Advances in psychiatry, neurology, and neurosurgery have given us fresh …

purpose. To determine whether structural plasticity is evident in human retinal tissues in
response to age-related macular degeneration (AMD). Remodeling events such as …

We consider the ethical and public policy implications of late recovery from the minimally
conscious state in light of an Institute of Medicine exploratory meeting convened to discuss …

Limited epidemiologic data undermine the identification of patients in a minimally con-scious
state (MCS) and needed health policy analysis. Based on the natural history of disorders of …

The assessment of patients with disorders of consciousness relies heavily upon the
subjective and consequently fallible interpretation of observed behaviour. Recent studies …