The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review

MD Klok, S Jakobsdottir, ML Drent - Obesity reviews, 2007 - Wiley Online Library
Leptin and ghrelin are two hormones that have been recognized to have a major influence
on energy balance. Leptin is a mediator of long‐term regulation of energy balance …

[PDF][PDF] Role of leptin in immunity

QL Lam, L Lu - Cell Mol Immunol, 2007 - cmi.ustc.edu.cn
Leptin, a protein hormone produced by the adipocytes, has long been recognized to
regulate metabolism, neuroendorine and other physiological functions. Early findings of …

Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention

D Iliopoulos, KN Malizos, A Tsezou - Annals of the rheumatic diseases, 2007 - ard.bmj.com
Objective: To investigate whether epigenetic mechanisms can regulate leptin's expression
and affect its downstream targets as metalloproteinases 3, 9, 13 in osteoarthritic …

Feeding and insulin increase leptin translation: Importance of the leptin mRNA untranslated regions

MJ Lee, RZ Yang, DW Gong, SK Fried - Journal of biological chemistry, 2007 - ASBMB
The post-transcriptional mechanisms by which feeding and insulin increase leptin
production are poorly understood. Starvation of 6–7-week-old rats for 14 h decreased leptin …

Developmental control of plasma leptin and adipose leptin messenger ribonucleic acid in the ovine fetus during late gestation: role of glucocorticoids and thyroid …

DM O'Connor, D Blache, N Hoggard, E Brookes… - …, 2007 - academic.oup.com
In developed countries, the increasing incidence of obesity is a serious health problem.
Leptin exposure in the perinatal period affects long-term regulation of appetite and energy …

Polymorphism of the porcine leptin gene promoter and analysis of its association with gene expression and fatness traits

M Stachowiak, M Mackowski, Z Madeja… - Biochemical …, 2007 - Springer
We describe for the first time a 245 bp fragment of the porcine leptin gene promoter in the
proximity of the transcription start site. Altogether, 720 pigs were screened with the PCR …

[PDF][PDF] Pharmacogenetic studies investigating the adverse effects of antipsychotics

H Lee - Psychiatry Investigation, 2007 - psychiatryinvestigation.org
The pharmacogenetic study of antipsychotics has been developed along with the
development of general techniques of genetic analysis. Because there are no significant …

Adipokines in osteoarthritis

N Presle, P Pottie, D Mainard, P Netter… - Osteoarthritis …, 2007 - books.google.com
Osteoarthritis (OA) is the most common joint disease in humans. It is a primary cause of
decreased activity in daily living and quality of life after middle age. This pathology affects …

低氧与ob 基因, 瘦素

雷雨, 崔丽萍, 朱党培 - 辽宁体育科技, 2007 - cqvip.com
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Contribution à l'étude bibliographique de la leptine chez les carnivores domestiques

B Faure - 2007 - oatao.univ-toulouse.fr
La leptine est une hormone polypeptidique polaire de 146 acides aminés découverte en
1994 par Zhang et al. Treize ans après, cette étude fait la synthèse des connaissances …