Medicinal importance of grapefruit juice and its interaction with various drugs

J Kiani, SZ Imam - Nutrition Journal, 2007 - Springer
Grapefruit juice is consumed widely in today's health conscious world as a protector against
cardiovascular diseases and cancers. It has however, been found to be an inhibitor of the …

Drug-drug and food-drug pharmacokinetic interactions with new insulinotropic agents repaglinide and nateglinide

AJ Scheen - Clinical pharmacokinetics, 2007 - Springer
This review describes the current knowledge on drug-drug and food-drug interactions with
repaglinide and nateglinide. These two meglitinide derivatives, commonly called glinides …

Grapefruit juice–drug interactions: Grapefruit juice and its components inhibit P‐glycoprotein (ABCB1) mediated transport of talinolol in Caco‐2 cells

WV De Castro, S Mertens‐Talcott, H Derendorf… - Journal of …, 2007 - Elsevier
To investigate the potential interaction between selected ingredients of grapefruit juice and,
the transport of talinolol, a P‐gp substrate, across Caco‐2 cells monolayers was determined …

Interacciones medicamentosas: aproximación para establecer y evaluar su relevancia clínica

P Amariles, NA Giraldo, MJ Faus - Medicina clínica, 2007 - Elsevier
La identificación, prevención y tratamiento de las interacciones medicamentosas
clínicamente relevantes son aspectos fundamentales en la farmacoterapia. En este trabajo …

Dose-effect study on the antioxidant properties of leaves and outer bracts of extracts obtained from Violetto di Toscana artichoke

R Coinu, S Carta, PP Urgeghe, N Mulinacci, P Pinelli… - Food Chemistry, 2007 - Elsevier
Artichoke (Cynara scolymus L.) is an edible vegetable largely used in the Mediterranean
diet and in folk medicine. The present paper discusses the analysis of the polyphenol …

Dietary fiber intake and endogenous serum hormone levels in naturally postmenopausal Mexican American women: the Multiethnic Cohort Study

KR Monroe, SP Murphy, BE Henderson, LN Kolonel… - HNUC, 2007 - Taylor & Francis
This study investigated dietary fiber intake in association with serum estrogen levels in
naturally postmenopausal Latina women with a wide range of fiber intake. Estrone (E1) …

Prospective study of grapefruit intake and risk of breast cancer in postmenopausal women: the Multiethnic Cohort Study

KR Monroe, SP Murphy, LN Kolonel, MC Pike - British journal of cancer, 2007 - nature.com
In vitro and in vivo studies have shown that cytochrome P450 3A4 (CYP3A4) is involved in
the metabolism of oestrogens. There is evidence that grapefruit, an inhibitor of CYP3A4 …

Absorption and pharmacokinetics of grapefruit flavanones in beagles

M de Lourdes Mata-Bilbao… - British journal of …, 2007 - cambridge.org
The present study evaluated the pharmacokinetics of three different grapefruit flavanone
forms in dog plasma and demonstrated their absorption after an oral intake of a grapefruit …

Different roles of pummelo furanocoumarin and cytochrome P450 3A5* 3 polymorphism in the fate and action of felodipine

LQ Guo, QY Chen, X Wang, YX Liu… - Current drug …, 2007 - ingentaconnect.com
Objective: Herein we aim to test if pummelo furanocoumarins can inhibit cytochrome P450
(CYP) 3A both in vitro and in vivo, and to explore the influence of CYP3A5* 3 (GenBank …

[PDF][PDF] Flavonoids in plants

J Janićijević, S Tošić, T Mitrović - Proceeding of the 9th Symposium on …, 2007 - sfses.com
Janićijević, J., Tošić, S., Mitrović, T.: Flavonoids in plants. Proceeding of the 9th Symposium
of flora of Southeastern Serbia and Neighbouring Regions, Nis, 2007. Flavonoids belong to …