Does androgen‐deprivation therapy accelerate the development of frailty in older men with prostate cancer? A conceptual review

K Bylow, SG Mohile, WM Stadler… - … International Journal of …, 2007 - Wiley Online Library
The majority of men with prostate cancer are aged≥ 65 years. Men, as they age, are more
likely to suffer from impaired physical function. The standard treatment for recurrent prostate …

The NF-κB/IL-6 pathway in metastatic androgen-independent prostate cancer: new therapeutic approaches?

B Paule, S Terry, L Kheuang, P Soyeux… - World journal of …, 2007 - Springer
The nuclear factor of kappa beta (NF-κB) transcription factor regulates the transcription of
numerous genes including that of interleukin 6 (IL-6). The IL-6 acts as an autocrine and …

An array of possibilities in cancer research using cytokine antibody arrays

RP Huang - Expert Review of Proteomics, 2007 - Taylor & Francis
Protein arrays have shown potential applications in cancer research. After several decades
of research, it has become evident that many cytokines are central to the development of …

The role of nuclear factor kappaB subunit p50 melanoma pathogenesis

K Gao - 2007 - open.library.ubc.ca
Transcriptional factor NF-κB family has been demonstrated to play an important role in tumor
pathogenesis and serve as a potential target in cancer therapy. However, it is necessary to …