The evolution of gene regulation by transcription factors and microRNAs
K Chen, N Rajewsky - Nature Reviews Genetics, 2007 - nature.com
Abstract Changes in the patterns of gene expression are widely believed to underlie many of
the phenotypic differences within and between species. Although much emphasis has been …
the phenotypic differences within and between species. Although much emphasis has been …
miRBase: tools for microRNA genomics
Abstract miRBase is the central online repository for microRNA (miRNA) nomenclature,
sequence data, annotation and target prediction. The current release (10.0) contains 5071 …
sequence data, annotation and target prediction. The current release (10.0) contains 5071 …
MicroRNA targeting specificity in mammals: determinants beyond seed pairing
Mammalian microRNAs (miRNAs) pair to 3′ UTRs of mRNAs to direct their
posttranscriptional repression. Important for target recognition are∼ 7 nt sites that match the …
posttranscriptional repression. Important for target recognition are∼ 7 nt sites that match the …
Mammalian mirtron genes
Mirtrons are alternative precursors for microRNA biogenesis that were recently described in
invertebrates. These short hairpin introns use splicing to bypass Drosha cleavage, which is …
invertebrates. These short hairpin introns use splicing to bypass Drosha cleavage, which is …
Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state
BD Brown, B Gentner, A Cantore, S Colleoni… - Nature …, 2007 - nature.com
We have shown previously that transgene expression can be suppressed in hematopoietic
cells using vectors that are responsive to microRNA (miRNA) regulation. Here we …
cells using vectors that are responsive to microRNA (miRNA) regulation. Here we …
miRNA profiling of naive, effector and memory CD8 T cells
microRNAs have recently emerged as master regulators of gene expression during
development and cell differentiation. Although profound changes in gene expression also …
development and cell differentiation. Although profound changes in gene expression also …
MicroRNA profiling: from dark matter to white matter, or identifying new players in neurobiology
AM Krichevsky - The Scientific World Journal, 2007 - Wiley Online Library
Contemporary biology has been revolutionized by a recently discovered class of small
regulatory RNA molecules, microRNAs (miRNAs). Missed by researchers for decades due to …
regulatory RNA molecules, microRNAs (miRNAs). Missed by researchers for decades due to …
Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa
CJ Loscher, K Hokamp, PF Kenna, AC Ivens… - Genome biology, 2007 - Springer
Background The role played by microRNAs (miRs) as common regulators in physiologic
processes such as development and various disease states was recently highlighted …
processes such as development and various disease states was recently highlighted …
Mouse cytomegalovirus microRNAs dominate the cellular small RNA profile during lytic infection and show features of posttranscriptional regulation
MicroRNAs (miRNAs) are small, noncoding RNA molecules that regulate gene expression
at the posttranscriptional level. Originally identified in a variety of organisms ranging from …
at the posttranscriptional level. Originally identified in a variety of organisms ranging from …
Discrete clusters of virus-encoded micrornas are associated with complementary strands of the genome and the 7.2-kilobase stable intron in murine cytomegalovirus
AH Buck, J Santoyo-Lopez, KA Robertson… - Journal of …, 2007 - Am Soc Microbiol
The prevalence and importance of microRNAs (miRNAs) in viral infection are increasingly
relevant. Eleven miRNAs were previously identified in human cytomegalovirus (HCMV); …
relevant. Eleven miRNAs were previously identified in human cytomegalovirus (HCMV); …