The role of pro-inflammatory cytokines in cancer treatment-induced alimentary tract mucositis: pathobiology, animal models and cytotoxic drugs
Alimentary tract (AT) mucositis can be a major problem for patients undergoing cancer
treatment. It has significant clinical and economic consequences and is a major factor that …
treatment. It has significant clinical and economic consequences and is a major factor that …
Mucositis: biology and management
N Treister, S Sonis - Current opinion in otolaryngology & head and …, 2007 - journals.lww.com
Mucositis is a common and serious complication secondary to chemoradiotherapy for head
and neck cancer that has a profound effect on morbidity, compliance and treatment …
and neck cancer that has a profound effect on morbidity, compliance and treatment …
Toward the definition of the mechanism of action of silymarin: activities related to cellular protection from toxic damage induced by chemotherapy
MC Comelli, U Mengs, C Schneider… - Integrative cancer …, 2007 - journals.sagepub.com
Silymarin, the active extract from milk thistle, has been extensively used in patients with liver
disease of different etiology. Although silymarin is a complex of 7 flavonolignans and …
disease of different etiology. Although silymarin is a complex of 7 flavonolignans and …
Intestinal mucositis: mechanisms and management
DM Keefe - Current opinion in oncology, 2007 - journals.lww.com
Intestinal mucositis: mechanisms and management : Current Opinion in Oncology Intestinal
mucositis: mechanisms and management : Current Opinion in Oncology Log in or Register …
mucositis: mechanisms and management : Current Opinion in Oncology Log in or Register …
Systemic and global toxicities of head and neck treatment
BA Murphy, J Gilbert, SH Ridner - Expert Review of Anticancer …, 2007 - Taylor & Francis
The increased use of aggressive, combined modality therapy for the treatment of head and
neck cancer has resulted in a marked increase in acute and late adverse effects. The acute …
neck cancer has resulted in a marked increase in acute and late adverse effects. The acute …
A novel animal model to investigate fractionated radiotherapy-induced alimentary mucositis: the role of apoptosis, p53, nuclear factor-κB, COX-1, and COX-2
Radiation-induced mucositis is a common and serious side effect of radiotherapy. Molecular
mechanisms of mucosal injury, however, are still poorly understood and extremely difficult to …
mechanisms of mucosal injury, however, are still poorly understood and extremely difficult to …
Gene expression analysis of multiple gastrointestinal regions reveals activation of common cell regulatory pathways following cytotoxic chemotherapy
Gastrointestinal mucositis involves many changes at the gene level, affecting
epithelial/subepithelial interactions and leading to overt damage. The regional specificity …
epithelial/subepithelial interactions and leading to overt damage. The regional specificity …