Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

C Szabó, H Ischiropoulos, R Radi - Nature reviews Drug discovery, 2007 - nature.com
Peroxynitrite—the product of the diffusion-controlled reaction of nitric oxide with superoxide
radical—is a short-lived oxidant species that is a potent inducer of cell death. Conditions in …

Biochemistry of protein tyrosine nitration in cardiovascular pathology

G Peluffo, R Radi - Cardiovascular research, 2007 - academic.oup.com
Several pathologies of the cardiovascular system are associated with an augmented
production of nitric oxide and/or superoxide-derived oxidants and/or alteration in the …

Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion

H Saba, I Batinic-Haberle, S Munusamy… - Free Radical Biology …, 2007 - Elsevier
Renal ischemia/reperfusion (I/R) injury often occurs as a result of vascular surgery, organ
procurement, or transplantation. We previously showed that renal I/R results in ATP …