Phosphoinositide (PI) 3-kinase is involved in insulin-mediated effects on glucose uptake,
lipid deposition, and adiponectin secretion from adipocytes. Genetic disruption of the p85α …

For decades, growth hormone (GH) has been known to influence electrolyte and water
handling in humans and animals. However, the molecular mechanisms underlying the GH …

Pituitary gigantism, a condition of endogenous growth hormone (GH) hypersecretion prior to
epiphyseal closure, is a rare condition. In the adult condition of GH excess, acromegaly, the …

Secondary diabetes mellitus is known to occur in acromegaly due to insulin resistance
caused by growth hormone excess. However diabetes in acromegaly usually does not lead …

Se l'acromegalia sia associata, o meno, ad un aumentato rischio di neoplasia rimane un
problema assai dibattuto. La mancanza di univocità della letteratura è riconducibile a diversi …

Although impaired glucose tolerance affects 36% and overt diabetes mellitus can be seen in
30% of cases with acromegaly, diabetic ketoacidosis is rarely reported in patients with this …

Myositis or inflammatory myopathy is a common but little-studied feature of acromegaly,
characterized by predominantly proximal weakness that can be accompanied by muscle …

Myositis or inflammatory myopathy is a common but little-studied feature of acromegaly,
characterized by predominantly proximal weakness that can be accompanied by muscle …