Focal therapy for localized prostate cancer: a critical appraisal of rationale and modalities

SE Eggener, PT Scardino, PR Carroll, MJ Zelefsky… - The Journal of …, 2007 - Elsevier
PURPOSE: Based on contemporary epidemiological and pathological characteristics of
prostate cancer we explain the rationale for and concerns about focal therapy for low risk …

Photodynamic molecular beacon as an activatable photosensitizer based on protease-controlled singlet oxygen quenching and activation

G Zheng, J Chen, K Stefflova, M Jarvi… - Proceedings of the …, 2007 - National Acad Sciences
Molecular beacons are FRET-based target-activatable probes. They offer control of
fluorescence emission in response to specific cancer targets, thus are useful tools for in vivo …

Indocyanine-green-embedded PEBBLEs as a contrast agent for photoacoustic imaging

G Kim, SW Huang, KC Day… - … of biomedical optics, 2007 - spiedigitallibrary.org
Nanoparticles 100 nm in diameter containing indocyanine green (ICG) have been
developed as a contrast agent for photoacoustic (PA) imaging based on (photonic explorers …

The future of lasers in urology

SA Pierre, DM Albala - World journal of urology, 2007 - Springer
The use of laser applications in urology has undergone significant advances over the past
20 years. Laser technology is now used in a wide variety of procedures, and has become …

In vivo optical characterization of human prostate tissue using near-infrared time-resolved spectroscopy

T Svensson, S Andersson-Engels… - … of biomedical optics, 2007 - spiedigitallibrary.org
The development of photodynamic therapy into a modality for treatment of prostate cancer
calls for reliable optical dosimetry. We employ, for the first time, interstitial time-resolved …

Realtime light dosimetry software tools for interstitial photodynamic therapy of the human prostate

A Johansson, J Axelsson, S Andersson‐Engels… - Medical …, 2007 - Wiley Online Library
Photodynamic therapy (PDT) for the treatment of prostate cancer has been demonstrated to
be a safe treatment option capable of inducing tissue destruction and decreasing prostate …

Interstitial photodynamic therapy for primary prostate cancer incorporating real-time treatment dosimetry

A Johansson, J Axelsson, J Swartling… - Optical Methods for …, 2007 - spiedigitallibrary.org
Photodynamic therapy (PDT) for the treatment of prostate cancer has been demonstrated to
be a safe treatment option capable of inducing tissue necrosis and decrease in prostate …

Hexyl‐aminolevulinate‐mediated photodynamic therapy: How to spare normal urothelium. An in vitro approach

L Vaucher, P Jichlinski, N Lange… - Lasers in Surgery …, 2007 - Wiley Online Library
Abstract Background and Objectives Photodynamic therapy (PDT) of superficial bladder
cancer may cause damages to the normal surrounding bladder wall. Prevention of these is …

Rational design of a receptor-targeted photodynamic molecular beacon for the multilevel control of singlet oxygen production and PDT activity in cancer cells

J Chen, K Stefflova, M Warren, J Bu… - … and Optical Probes …, 2007 - spiedigitallibrary.org
Photodynamic therapy (PDT) involves the combined action of light, oxygen and a
photosensitizer (PS). It offers unique control in the PS's action because the key cytotoxic …

Vascular-targeted photodynamic of prostate cancer phase with Tookad for recurrent prostate cancer following radiation therapy: initial clinical studies

RA Weersink, BC Wilson, A Bogaards… - … and Diagnostics III, 2007 - spiedigitallibrary.org
We report on the first clinical application of vascular-targeted photodynamic therapy using a
bacteriopheophorbide derivative, Tookad, in patients with localized prostate cancer …