[HTML][HTML] Effect of inhibition of dynein function and microtubule-altering drugs on AAV2 transduction

S Hirosue, K Senn, N Clément, M Nonnenmacher… - Virology, 2007 - Elsevier
Over the past decade, adeno-associated (AAV) virus has emerged as an important vector for
gene therapy. As a result, understanding its basic biology, including intracellular trafficking …

Notch1 augments intracellular trafficking of adeno-associated virus type 2

C Ren, AF White, S Ponnazhagan - Journal of virology, 2007 - Am Soc Microbiol
We report here the significance of the Notch1 receptor in intracellular trafficking of
recombinant adeno-associated virus type 2 (rAAV2). RNA profiling of human prostate cancer …

[图书][B] Mechanisms of entry and superinfection of equine infectious anemia virus

MA Brindley - 2007 - search.proquest.com
Equine infectious anemia virus (EIAV) is a lentivirus related to HIV. The mechanism of EIAV
entry has not been previously explored and we have sought to determine if EIAV fuses at the …

Modulation of the Immune Response by Targeting Endothelial Cells

M Manunta, P Hong Tan… - Anti-Inflammatory & …, 2007 - ingentaconnect.com
Although endothelial cells are not immunological cells in sensu stricto, they play an
important role in controlling inflammation/immune responses. The endothelium is involved in …

[图书][B] The development of viral vectors for targeted gene delivery to atherosclerotic plaques

K White - 2007 - search.proquest.com
Cardiovascular disease is one of the leading causes of death in the Western world. One of
the most common causes is the rupture of unstable atherosclerotic plaques, which can lead …

[图书][B] Funktionelle Charakterisierung des Parvovirus H-1 Capsids während des Infektionsvorganges

H Ahrens - 2007 - jlupub.ub.uni-giessen.de
Parvoviren sind kleine nichtumhüllte weitverbreitete Viren und kommen bei praktisch allen
Tierarten und beim Menschen vor. Sie werden über Endozytose in die Zelle aufgenommen …

[图书][B] Adeno-associated virus vector mediated correction of a neurogenetic disease: Influence of the vector capsid on dispersal of a therapeutic gene within the …

CN Cearley - 2007 - search.proquest.com
Genetic disorders of the brain can be debilitating, causing both cognitive and motor
impairments, and often resulting in premature death. Despite this, there are very few …

Mapping of Adeno-Associated Virus 2 Immunogenic Epitopes and Cellular Receptor Binding Sites-Improving a Gene Therapy Vector

W Bu - 2007 - diginole.lib.fsu.edu
Monoclonal antibody (mAb) A20 is the best characterized AAV2 neutralizing mAb [18, 116,
165]. Large quantities of the mAb A20 were obtained from hybridomas cell culture, and A20 …