LDL has been widely recognized as the major atherogenic lipoprotein and designated as
the primary target for prevention of coronary heart disease (CHD); however, there is growing …

The aim of this study was to explore potential herb–drug interaction between baicalin and
rosuvastatin, a typical substrate for organic anion‐transporting polypeptide 1B1 (OATP1B1) …

Objective: Lipid profiling (lipidomics) may be useful in revealing detailed information with
regard to the effects on lipid metabolism, the cardiovascular risk and to differentiate between …

Background: The HMG Co-A reductase inhibitors (statins) are the most efficacious agents for
lowering cholesterol. Statins reduce clinical cardiovascular events and are generally well …

Rosuvastatin is a relatively new member of the statin family (HMG-CoA reductase inhibitors),
with superior lipid-lowering effects and a pattern of clinical side effects, including a low …

The study evaluated the effect of the traditional Chinese medicine rhubarb on the stability of
atherosclerotic plaque. Atherosclerotic lesions were induced in rabbits through balloon …

We investigated whether chronic rosuvastatin administration could improve the
abnormalities of the circulating levels of vascular dysfunction markers in pulmonary arterial …

A rapid and sensitive high‐performance liquid chromatographic method was developed and
validated for the simultaneous determination and quantification of atenolol, rosuvastatin …

Expression of the organic anion transporting polypeptide 1B1 (OATP1B1) is regulated by
transcription factor hepatic nuclear factor (HNF) 1α. The aim of this study was to investigate …

ABSTRACT Objective: Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)
reductase inhibitor used for the treatment of dyslipidaemia, may be co-administered with …