In the last decade, there has been an increase in interest in the burden of chronic and
disabling health conditions that are not necessarily fatal, such as the mental disorders. This …

Context There are no studies of the natural history of major depressive disorder that lack
prevalence and clinic biases. Objectives To estimate risk factors for first lifetime onset and …

Objectives. The objective of this study was to evaluate the impact of driving cessation on
social integration and perceived support from relatives and friends among older adults …

Context Depression is common in old age. Nevertheless, few incidence studies have
established how often depression occurs in elderly persons with and without a history of …

Objective To estimate the projected population of US adults aged 18 years or older with
lifetime experience of doctor‐diagnosed depressive disorder from 2005–2050. Methods …

Objectives. We investigated the association between major depressive disorder and type 2
diabetes, whether that association is explained by health behaviors, and whether it is …

Background: Previous studies that have assessed whether the presence of depressive
symptoms predisposes to stroke in the general elderly population have been contradictory …

Background No previous studies on the effect of genetic factors on the liability to disability
retirement have been carried out. The main aim of this study was to investigate the …

The nature of the relationship between affective disorders, bone mineral density (BMD), and
bone metabolism is unresolved, although there is growing evidence that many medications …

Publisher Summary Depression is part of a category of more common, complex disorders
where several or many genes are implicated, each of which has only a modest effect on its …