Page 1 The National Colla C for Chronic Condition OSTEOARTHRITIS National clinical
guideline for care and management in adults Royal College of Physicians Page 2 The National …

Aims: To determine the risks of cardiac failure with non‐steroidal anti‐inflammatory drugs
(NSAIDs) and the specific risks with Cox‐2 specific NSAIDs (COXIBs). Methods: We …

Objective To compare the clinical presentation, management, and outcome of heart failure in
patients with rheumatoid arthritis (RA) compared with non‐RA patients. Methods We …

Background. Knowledge of any harm associated with living kidney donation guides
informed consent and living donor follow-up. Risk estimates in the literature are variable …

New series of 2-(4-methylsulfonylphenyl) and 2-(4-sulfamoylphenyl) pyrimidines were
synthesized and evaluated for their ability to inhibit cyclooxygenase-2 (COX-2). COX-1 and …

The limited success of current treatments for most advanced common malignancies
highlights the importance of cancer prevention. Clinical trials on cyclooxygenase (COX) …

Objective: Limited evidence suggests that selective serotonin reuptake inhibitor (SSRI)
antidepressants can hinder platelet aggregation and can increase the risk of hemorrhage …

Inflammation underlies the pathogenesis of many common cardiovascular diseases (CVD)
such as myocardial infarction, atherosclerosis, myocarditis and dilated cardiomyopathy …

Cyclooxygenase-2 (cox-2) inhibitors, also known as coxibs, were introduced with the
promise that they would provide pain relief similar to that of traditional nonsteroidal anti …

BACKGROUND: Heart failure is a major cause of morbidity and mortality and is increasing in
prevalence. Treatments for heart failure permit a growing number of persons to live with the …