Defining responses to therapy and study outcomes in clinical trials of invasive fungal diseases: Mycoses Study Group and European Organization for Research and …

BH Segal, R Herbrecht, DA Stevens… - Clinical infectious …, 2008 - academic.oup.com
Invasive fungal diseases (IFDs) have become major causes of morbidity and mortality
among highly immunocompromised patients. Authoritative consensus criteria to diagnose …

Voriconazole in the treatment of fungal eye infections: a review of current literature

SM Hariprasad, WF Mieler, TK Lin… - British Journal of …, 2008 - bjo.bmj.com
Background: Voriconazole has an important role to play in the prophylaxis and management
of fungal endophthalmitis and keratitis. New-generation triazoles, including voriconazole …

Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America

TJ Walsh, EJ Anaissie, DW Denning, R Herbrecht… - Clinical infectious …, 2008 - JSTOR
Aspergillus species have emerged as an important cause of life-threatening infections in
immunocompromised patients. This expanding population is composed of patients with …

Significant alterations in the epidemiology and treatment outcome of invasive fungal infections in patients with hematological malignancies

J Auberger, C Lass-Flörl, H Ulmer… - International journal of …, 2008 - Springer
Invasive fungal infections (IFI) remain a leading cause of morbidity and mortality in
immunocompromised patients. This retrospective single-center study analyzed incidence …

Pulmonary aspergillosis

GR Thompson, TF Patterson - Seminars in Respiratory and …, 2008 - thieme-connect.com
As the population of patients with prolonged neutropenia, those receiving hematopoietic
stem cell transplantation or lung transplantation, or those with human immunodeficiency …

When primary antifungal therapy fails

M Nucci, JR Perfect - Clinical infectious diseases, 2008 - academic.oup.com
The prognosis for persons with invasive fungal infections has improved over the past 2
decades because of the development of new diagnostic tools, a better understanding of the …

Current options in antifungal pharmacotherapy

J Mohr, M Johnson, T Cooper, JS Lewis… - … : The Journal of …, 2008 - Wiley Online Library
Infections caused by yeasts and molds continue to be associated with high rates of morbidity
and mortality in both immunocompromised and immunocompetent patients. Many antifungal …

Changes in causes of death over time after treatment for invasive aspergillosis

JR Wingard, P Ribaud, HT Schlamm, R Herbrecht - Cancer, 2008 - Wiley Online Library
BACKGROUND Assessment of response to invasive aspergillosis (IA) therapy has been
challenging in treatment trials. METHODS The causes of death over 12 weeks were …

Fungal infections in hematopoietic stem cell transplant recipients

KA Marr - Medical mycology, 2008 - academic.oup.com
Fungal infections have historically been, and remain important causes of transplant-related
morbidity in recipients of hematopoietic stem cell transplant (HSCT). However, there have …

Advances in antifungal therapy

CA Sable, KM Strohmaier, JA Chodakewitz - Annu. Rev. Med., 2008 - annualreviews.org
The prevalence of invasive fungal infections (IFIs) has increased over the past three
decades owing to the increasing numbers of immunocompromised hosts. These infections …