Barriers to recruiting underrepresented populations to cancer clinical trials: a systematic review

JG Ford, MW Howerton, GY Lai, TL Gary… - … journal of the …, 2008 - Wiley Online Library
Racial and ethnic minorities, older adults, rural residents, and individuals of low
socioeconomic status are underrepresented among participants in cancer‐related trials. The …

Cancer survivorship and aging

NE Avis, GT Deimling - … journal of the american cancer society, 2008 - Wiley Online Library
Cancer is primarily a disease of the elderly. Greater than 60% of new cancers occur in
people aged> 65 years, and 60% of the current 10 million cancer survivors are aged≥ 65 …

Age and gender are significant independent predictors of survival in primary cutaneous melanoma

K Lasithiotakis, U Leiter, F Meier… - … Journal of the …, 2008 - Wiley Online Library
BACKGROUND The aim was to identify age‐related and gender‐related differences in the
clinical presentation and outcome of patients with primary cutaneous melanoma (CM) …

Controversies of total mesorectal excision for rectal cancer in elderly patients

HJT Rutten, M den Dulk, VEPP Lemmens… - The lancet …, 2008 - thelancet.com
The cornerstone of treatment for rectal cancer is resectional treatment according to the
principles of total mesorectal excision (TME). However, population-based registries show …

Erlotinib for advanced non–small-cell lung cancer in the elderly: an analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR. 21

P Wheatley-Price, K Ding, L Seymour… - Journal of Clinical …, 2008 - ascopubs.org
Purpose National Cancer Institute of Canada Clinical Trials Group Study BR. 21 established
erlotinib as a standard of care in patients with non–small-cell lung cancer (NSCLC) after …

Does a geriatric oncology consultation modify the cancer treatment plan for elderly patients?

V Girre, MC Falcou, M Gisselbrecht… - The Journals of …, 2008 - academic.oup.com
Background. This study was performed to describe the treatment plan modifications after a
geriatric oncology clinic. Assessment of health and functional status and cancer assessment …

A randomised multicentre phase II trial of capecitabine vs S-1 as first-line treatment in elderly patients with metastatic or recurrent unresectable gastric cancer

JL Lee, YK Kang, HJ Kang, KH Lee, DY Zang… - British journal of …, 2008 - nature.com
This randomised multicentre phase II study was conducted to investigate the activity and
safety of two oral fluoropyrimidines, capecitabine or S-1, in elderly patients with advanced …

[HTML][HTML] Improvements in survival of adults diagnosed with acute myeloblastic leukemia in the early 21st century

D Pulte, A Gondos, H Brenner - Haematologica, 2008 - haematologica.org
Abstract Treatment of adults with acute myeloblastic leukemia has changed substantially
over the past two decades. Currently available estimates of survival do not reflect results …

Pemetrexed plus carboplatin in elderly patients with malignant pleural mesothelioma: combined analysis of two phase II trials

GL Ceresoli, B Castagneto, PA Zucali… - British journal of …, 2008 - nature.com
The incidence of malignant pleural mesothelioma (MPM) in elderly patients is increasing. In
this study, pooled data from two phase II trials of pemetrexed and carboplatin (PC) as first …

Role of age and health in treatment recommendations for older adults with breast cancer: the perspective of oncologists and primary care providers

A Hurria, FL Wong, D Villaluna, S Bhatia… - Journal of clinical …, 2008 - ascopubs.org
Purpose To determine the impact of age and health status on adjuvant treatment
recommendations for older patients with breast cancer from the perspective of medical …