Factors in the pathophysiology of the liver ischemia-reperfusion injury
EE Montalvo-Jave, T Escalante-Tattersfield… - Journal of Surgical …, 2008 - Elsevier
Hepatic ischemia-reperfusion injury is commonplace in liver surgery, particularly in hepatic
transplantation, hepatic resection, and trauma. The signaling events contributing to local …
transplantation, hepatic resection, and trauma. The signaling events contributing to local …
Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis
N Anderson, J Borlak - Pharmacological reviews, 2008 - ASPET
Steatosis of the liver may arise from a variety of conditions, but the molecular basis for lipid
droplet formation is poorly understood. Although a certain amount of lipid storage may even …
droplet formation is poorly understood. Although a certain amount of lipid storage may even …
[HTML][HTML] The importance of immune dysfunction in determining outcome in acute liver failure
CG Antoniades, PA Berry, JA Wendon, D Vergani - Journal of hepatology, 2008 - Elsevier
Acute liver failure (ALF) shares striking similarities with septic shock with regard to the
features of systemic inflammation, progression to multiple organ dysfunction and functional …
features of systemic inflammation, progression to multiple organ dysfunction and functional …
[PDF][PDF] The impact of postreperfusion syndrome on short‐term patient and liver allograft outcome in patients undergoing orthotopic liver transplantation
I Hilmi, CN Horton, RM Planinsic, T Sakai… - Liver …, 2008 - Wiley Online Library
The greatest part of liver allograft injury occurs during reperfusion, not during the cold
ischemia phase. The aim of this study, therefore, was to investigate how the severity of …
ischemia phase. The aim of this study, therefore, was to investigate how the severity of …
Molecular mediators of liver ischemia and reperfusion injury: a brief review
AJ Vardanian, RW Busuttil, JW Kupiec-Weglinski - Molecular Medicine, 2008 - Springer
Ischemia and reperfusion injury is a dynamic process that involves multiple organ systems in
various clinical states including transplantation, trauma, and surgery. Research into this field …
various clinical states including transplantation, trauma, and surgery. Research into this field …
[PDF][PDF] Hepatocyte signaling through CXC chemokine receptor‐2 is detrimental to liver recovery after ischemia/reperfusion in mice
S Kuboki, T Shin, N Huber, T Eismann, E Galloway… - …, 2008 - Wiley Online Library
CXC chemokines and their receptor, CXC chemokine receptor‐2 (CXCR2), are important
components of the hepatic inflammatory response to ischemia/reperfusion (I/R). However …
components of the hepatic inflammatory response to ischemia/reperfusion (I/R). However …
Reciprocal activation between CD4+ T cells and Kupffer cells during hepatic ischemia-reperfusion
M Hanschen, S Zahler, F Krombach… - Transplantation, 2008 - journals.lww.com
Background. Mechanisms mediating CD4+ T-cell recruitment during alloantigen-
independent hepatic ischemia-reperfusion (I/R) remain not fully understood. We …
independent hepatic ischemia-reperfusion (I/R) remain not fully understood. We …
Modulation of cardiac and hepatic cytochrome P450 enzymes during heart failure
AOS El-Kadi, BNM Zordoky - Current drug metabolism, 2008 - ingentaconnect.com
Heart failure is a very serious cardiovascular disease that affects more than five million
people in North America. The role of cytochrome P450 (CYP) in cardiovascular health and …
people in North America. The role of cytochrome P450 (CYP) in cardiovascular health and …
Inhibition of COX 1 and 2 prior to renal ischemia/reperfusion injury decreases the development of fibrosis
CQ Feitoza, GM Gonçalves, P Semedo… - Molecular …, 2008 - Springer
Ischemia and reperfusion injury (IRI) contributes to the development of chronic interstitial
fibrosis/tubular atrophy in renal allograft patients. Cyclooxygenase (COX) 1 and 2 actively …
fibrosis/tubular atrophy in renal allograft patients. Cyclooxygenase (COX) 1 and 2 actively …
[HTML][HTML] Oxidative stress: a radical way to stop making bile
MG Roma, EJS Pozzi - Annals of Hepatology, 2008 - Elsevier
Oxidative stress is a common feature in most hepatopathies. In recent years, evidence has
accumulated that reactive oxygen species (ROS) induce a number of functional changes …
accumulated that reactive oxygen species (ROS) induce a number of functional changes …