The chemokine receptor CXCR3 is expressed on the surface of both resting and activated T
lymphocytes. We describe in this study the endocytosis of CXCR3 using T lymphocytes and …

Oeosinophils are pleiotropic multi-functional leukocytes that are typically associated with the
initiation and propagation of inflammatory responses, particularly helminth infection and …

Given the central role of chemokines in infection, inflammation and immunity, chemokine
receptors are a prime target for pharmacological intervention, and more so after the recent …

The interaction between CC chemokine receptor 2 (CCR2) with monocyte chemoattractant
proteins, such as MCP-1, regulates the activation and recruitment of inflammatory …

Chemokines play a key role in immune processes by controlling leukocyte recruitment in
physiological and pathological condition. This review discusses the regulation of the …

The interaction between CC chemokine receptor 2 (CCR2) with monocyte chemoattractant
proteins, such as MCP-1, regulates the activation and recruitment of inflammatory …

Asthma is a chronic-inflammatory disease of the airways and about 15% of the population in
the industrialized countries suffer from it. The characteristic inflammation of the lung is …

Allergen-induced inflammation manifests as allergic asthma, dermatitis, rhinitis,
conjunctivitis, food allergies, and life-threatening anaphylaxis. Allergic reactions consist of …

In Bezug auf die allosterische Bindungsstelle G-Protein-gekoppelter Rezeptoren sind
muskarinische Acetylcholinrezeptoren die am besten untersuchte Rezeptor-Familie. Da die …

Eosinophilic gastrointestinal disorders are rare inflammatory diseases of unknown origin
defined as disorders that selectively affect the gastrointestinal tract with eosinophil-rich …