Sudden cardiac death and acute myocardial infarction often occur as the first manifestation
of coronary artery disease. Otherwise asymptomatic individuals with subclinical …

The discovery of vascular endothelial growth factors (VEGFs) and their receptors has
considerably improved the understanding of the development and function of endothelial …

BACKGROUND: Carotid endarterectomy is beneficial in severe (> 70%) symptomatic carotid
stenosis. The risk of stroke in moderate carotid stenosis (50%-69%) is modest, and so the …

BACKGROUND: Magnetic resonance imaging (MRI) can noninvasively assess changes in
atherosclerotic plaque morphology and composition. The ORION trial assessed the effects of …

Background and Purpose—Advances in carotid plaque imaging could allow quantification of
fibrous cap thickness in vivo. While a cap thickness< 65 μm is the accepted definition of …

Objectives: Studies were performed to develop a prolonged antiangiogenesis therapy
regimen based on theranostic ανβ3-targeted nanoparticles. Background: Antiangiogenesis …

PURPOSE: Increased risk of atherosclerosis and stroke has been demonstrated in patients
receiving radiotherapy for Hodgkin's lymphoma and head-and-neck cancer. We previously …

Background and Purpose—Atheroma vulnerability to rupture is increased in the presence of
a large lipid core. Factors associated with a lipid core in the general population have not …

The adventitia and the outer layers of media of an atherosclerosis-prone arterial wall are
vascularized by vasa vasorum. Upon growth of an atherosclerotic lesion in the intima …

Objectives: Via magnetic resonance imaging (MRI), we sought to determine the prevalence
of atherosclerotic American Heart Association type VI lesions (AHA-LT6)(lesions with …