Cell and biomolecular mechanics in silico
AA VAziri, AV GopinAth - Nature materials, 2008 - nature.com
Recent developments in computational cell and biomolecular mechanics have provided
valuable insights into the mechanical properties of cells, subcellular components and …
valuable insights into the mechanical properties of cells, subcellular components and …
The effect of geometry on three-dimensional tissue growth
M Rumpler, A Woesz, JWC Dunlop… - Journal of the …, 2008 - royalsocietypublishing.org
Tissue formation is determined by uncountable biochemical signals between cells; in
addition, physical parameters have been shown to exhibit significant effects on the level of …
addition, physical parameters have been shown to exhibit significant effects on the level of …
Endothelial cell–matrix interactions in neovascularization
ME Francis, S Uriel, EM Brey - Tissue Engineering Part B: Reviews, 2008 - liebertpub.com
The success of many therapies in regenerative medicine requires the ability to control the
formation of stable vascular networks within tissues. The formation of new blood vessels, or …
formation of stable vascular networks within tissues. The formation of new blood vessels, or …
[HTML][HTML] Tissue deformation modulates twist expression to determine anterior midgut differentiation in Drosophila embryos
N Desprat, W Supatto, PA Pouille, E Beaurepaire… - Developmental cell, 2008 - cell.com
Mechanical deformations associated with embryonic morphogenetic movements have been
suggested to actively participate in the signaling cascades regulating developmental gene …
suggested to actively participate in the signaling cascades regulating developmental gene …
Osteocyte morphology in fibula and calvaria—is there a role for mechanosensing?
INTRODUCTION: External mechanical forces on cells are known to influence cytoskeletal
structure and thus cell shape. Mechanical loading in long bones is unidirectional along their …
structure and thus cell shape. Mechanical loading in long bones is unidirectional along their …
Two characteristic regimes in frequency-dependent dynamic reorientation of fibroblasts on cyclically stretched substrates
S Jungbauer, H Gao, JP Spatz, R Kemkemer - Biophysical journal, 2008 - cell.com
Cells adherent on a cyclically stretched substrate with a periodically varying uniaxial strain
are known to dynamically reorient nearly perpendicular to the strain direction. We …
are known to dynamically reorient nearly perpendicular to the strain direction. We …
[HTML][HTML] Scaffold stiffness influences cell behavior: opportunities for skeletal tissue engineering
RGM Breuls, TU Jiya, TH Smit - The open orthopaedics journal, 2008 - ncbi.nlm.nih.gov
Skeletal defects resulting from trauma, tumors, or abnormal development frequently require
surgical treatment to restore normal tissue function. To overcome the limitations associated …
surgical treatment to restore normal tissue function. To overcome the limitations associated …
[HTML][HTML] Mechano-coupling and regulation of contractility by the vinculin tail domain
Vinculin binds to multiple focal adhesion and cytoskeletal proteins and has been implicated
in transmitting mechanical forces between the actin cytoskeleton and integrins or cadherins …
in transmitting mechanical forces between the actin cytoskeleton and integrins or cadherins …
Enhancement of in vitro capillary tube formation by substrate nanotopography
CJ Bettinger, Z Zhang, S Gerecht… - Advanced …, 2008 - Wiley Online Library
Endothelial progenitor cells are cultured on nanotopographic substrates with a line‐grating
geometry and respond to these substrates through aligned and elongated morphology …
geometry and respond to these substrates through aligned and elongated morphology …
Engineered nanoforce gradients for inhibition of settlement (attachment) of swimming algal spores
JF Schumacher, CJ Long, ME Callow, JA Finlay… - Langmuir, 2008 - ACS Publications
Current antifouling strategies are focused on the development of environmentally friendly
coatings that protect submerged surfaces from the accumulation of colonizing organisms (ie …
coatings that protect submerged surfaces from the accumulation of colonizing organisms (ie …