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Sepsis is a systemic response to infection, and symptoms are produced by host defense
systems rather than by the invading pathogens. Amongst the most prominent features of …

Leukocyte-derived microparticles (MPs) are markers of cardiovascular diseases and
contribute to pathogenesis by their interaction with various cell types. The presence and …

Platelets have long been recognized to be of central importance in haemostasis, but their
participation in pathological conditions such as thrombosis, atherosclerosis and …

Cell activation or apoptosis leads to plasma membrane blebbing and microparticle (MP)
release in the extracellular space. MPs are submicron membrane vesicles which express a …

Both inflammation and thrombosis can be orchestrated by the interactions between
circulating cells, such as leukocytes and platelets, with vascular, endothelial and smooth …

Cell membrane microparticles (MPs) are phospholipid microvesicles shed from the plasma
membrane of most eukaryotic cells undergoing activation or apoptosis. The presence of MPs …

Tissue factor pathway inhibitor (TFPI) is a potent anticoagulant protein that abrogates the
activity of the tissue factor-factor VIIa catalytic complex that activates blood coagulation in …

Microparticles (MPs) are small fragments of membrane-bound cytoplasm that are shed from
the surface of an activated or apoptotic cell. Recently, their function as vectors of …

Background: Splenectomy is frequently employed for therapeutic and diagnostic purposes in
various clinical disorders. However its long-term safety is not well elucidated. Although risk …