Pharmacokinetics/pharmacodynamics of antibacterials in the Intensive Care Unit: setting appropriate dosing regimens

F Scaglione, L Paraboni - International journal of antimicrobial agents, 2008 - Elsevier
Patients admitted to Intensive Care Units (ICUs) are at very high risk of developing severe
nosocomial infections. Consequently, antimicrobials are among the most important and …

Alveolar concentrations of piperacillin/tazobactam administered in continuous infusion to patients with ventilator-associated pneumonia

E Boselli, D Breilh, T Rimmelé, C Guillaume… - Critical care …, 2008 - journals.lww.com
Objectives: To determine the steady-state serum and alveolar concentrations of piperacillin/
tazobactam administered in continuous infusion to critically ill patients with ventilator …

Novel approach to the eradication of Pseudomonas aeruginosa in an infant with CF after outpatient treatment failure

D Hayes Jr, JF Kanga, MI Anstead… - Pediatric …, 2008 - Wiley Online Library
Intravenous continuous infusion of betalactam (CIBL) antibiotic and high dose extended
interval (HDEI) aminoglycoside therapy theoretically maximize bacterial killing in treatment …