[HTML][HTML] Calcium-independent and 1, 25 (OH) 2D3-dependent regulation of the renin-angiotensin system in 1α-hydroxylase knockout mice

C Zhou, F Lu, K Cao, DI Xu, D Goltzman, D Miao - Kidney international, 2008 - Elsevier
To determine whether the cardiovascular effect of 1, 25 (OH) 2 D is dependent on calcium
and/or phosphorus, mice with targeted deletion of the 25 (OH) D 1α-hydroxylase and their …

Renin inhibitor aliskiren improves impaired nitric oxide bioavailability and protects against atherosclerotic changes

T Imanishi, H Tsujioka, H Ikejima, A Kuroi… - …, 2008 - Am Heart Assoc
We investigated whether aliskiren, a direct renin inhibitor, improves NO bioavailability and
protects against spontaneous atherosclerotic changes. We also examined the effects of …

The potential role of angiotensin converting enzyme and vasopeptidase inhibitors in the treatment of diabetic neuropathy

MA Yorek - Current Drug Targets, 2008 - ingentaconnect.com
Diabetic neuropathy is a debilitating disorder that occurs in more than 50 percent of patients
with diabetes. Evidence suggests that there are at least five major pathways involved in the …

Angiotensin I-converting enzyme inhibitor activity of nutritive plants in KwaZulu-Natal

S Ramesar, H Baijnath, T Govender… - Journal of medicinal …, 2008 - liebertpub.com
Traditional herbal remedies still form an integral part of South African culture, hence
necessitating reports on the scientific rationale for their uses. Organic and aqueous extracts …

Establishing a new option for target-organ protection: rationale for ARB plus ACE inhibitor combination therapy

JN Cohn, JM Goldman - American journal of hypertension, 2008 - academic.oup.com
Activation of the renin–angiotensin system (RAS) plays an important role in the promotion of
cardiovascular disease and target-organ damage, mediated in part by hypertension …

Perinatal 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure Sensitizes Offspring to Angiotensin II-induced Hypertension

AC Aragon, MB Goens, E Carbett, MK Walker - Cardiovascular toxicology, 2008 - Springer
In utero and lactational exposure of mice to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
leads to cardiac hypertrophy and hydronephrosis in adulthood. We tested the hypothesis …

The in vivo effects of Tulbhagia violacea on blood pressure in a salt-sensitive rat model

I Mackraj, S Ramesar, M Singh, T Govender… - Journal of …, 2008 - Elsevier
AIM OF THE STUDY: The in vivo effects of Tulbhagia violacea on systemic arterial blood
pressure and on the renin-angiotensin system in a Dahl salt-sensitive rat model were …

Perindopril for control of blood pressure in patients with hypertension and other cardiovascular risk factors: an open-label, observational, multicentre, general practice …

RI Ogilvie, S Anand, P Roy, S De Souza - Clinical Drug Investigation, 2008 - Springer
Background and objectives: Hypertension, one of the major treatable cardiovascular (CV)
risk factors, usually occurs in association with other major risk factors. As well as providing …

Evidence of α1‐adrenoceptor functional changes in omental arteries of patients with end‐stage renal disease

MP Cruz‐Domínguez… - Autonomic and …, 2008 - Wiley Online Library
Summary 1α1‐Adrenoceptor (α1‐AR) subtypes were characterized in isolated omental
arteries obtained after abdominal surgery in patients with end‐stage renal disease (ESRD) …

[PDF][PDF] Sindrome cardiorrenal

AH Aréstegui - Rev Peru Cardiol [Internet], 2008 - sisbib.unmsm.edu.pe
El termino “cardiorenal” ha sido utilizado en la literatura medica para describir la conexión
hemodinámica y neurohormonal que existe entre el corazón y riñón (1). Históricamente fue …